LINC01490: A Potential Drug Target and Biomarker (G101928420)

Target Name: LINC01490

NCBI ID: G101928420

LINC01490

Other Name(s): Long intergenic non-protein coding RNA 1490, transcript variant 1 | long intergenic non-protein coding RNA 1490

LINC01490: A Potential Drug Target and Biomarker

Abstract

LINC01490 is a long intergenic non-protein coding RNA (lncRNA) with a unique transcript variant identification number (TVD) of 1. It is a non-coding RNA that has been identified to be involved in various cellular processes, including cell adhesion, migration, and survival. Furthermore, LINC01490 has been shown to play a role in the development and progression of various diseases, such as cancer. This article will discuss the potential implications of LINC01490 as a drug target and biomarker.

Long non-coding RNAs (lncRNAs) have emerged as a promising candidate for drug targeting and biomarkers due to their diverse functions and the potential to disrupt gene expression networks. LINC01490 is one of these lncRNAs that has gained significant interest due to its unique features and the evidence supporting its involvement in various biological processes.

Expression and Localization

LINC01490 is a long non-coding RNA that has been identified in various cellular compartments, including the nucleus, cytoplasm, and endoplasmic reticulum (ER). It is expressed in a variety of cell types and has been shown to play a role in cell adhesion, migration, and survival.

Additionally, LINC01490 has been shown to localize to specific protein-coding genes, including the neural stem cell marker PDGFRA. This localization suggests that LINC01490 may be involved in the regulation of gene expression and could potentially serve as a drug target or biomarker.

Function and Implications

The functions of LINC01490 are still being explored, but evidence suggests that it plays a role in the development and progression of various diseases, including cancer. For example, studies have shown that LINC01490 is highly expressed in various cancer types and that it is associated with poor prognosis in cancer patients.

Furthermore, LINC01490 has been shown to be involved in the regulation of cell adhesion and migration, which are critical processes for the development of cancer. For instance, LINC01490 has been shown to play a role in the regulation of tight junction formation, a process that is critical for maintaining the integrity of the blood-brain barrier.

Drug Targeting

The potential drug targeting of LINC01490 is based on its unique functions and the evidence suggesting that it plays a role in various cellular processes that are associated with the development and progression of disease.

One potential drug target for LINC01490 is the inhibition of its expression, as this could potentially reduce its levels and disrupt its functions. Additionally, drugs that specifically target the translation of LINC01490 into protein could also be a potential drug target.

Biomarker

The potential use of LINC01490 as a biomarker for disease diagnosis and monitoring has also been explored. The high expression of LINC01490 in various diseases, including cancer, suggests that it may be a useful biomarker for these diseases.

Furthermore, LINC01490 has been shown to play a role in the regulation of cell adhesion and migration, which are critical processes for the development of cancer. Therefore, LINC01490 may be a useful biomarker for monitoring the effectiveness of anti-cancer drugs.

Conclusion

In conclusion, LINC01490 is a long non-coding RNA that has been identified to play a role in various cellular processes, including cell adhesion, migration, and survival. Its unique expression and localization to specific protein-coding genes suggest that it may be a potential drug target or biomarker. Further research is needed to fully understand the functions of LINC01490 and its potential as a drug target or biomarker

Protein Name: Long Intergenic Non-protein Coding RNA 1490

The "LINC01490 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LINC01490 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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