MIR6746: A Promising Drug Target and Biomarker for Cancer (G102465446)
MIR6746: A Promising Drug Target and Biomarker for Cancer
MIR6746 (hsa-miR-6746-3p) is a microRNA (miRNA) that has been identified as a potential drug target and biomarker for various diseases, including cancer. Its unique structure and specificity make it an attractive target for drug development due to its ability to regulate gene expression and contribute to the development of various diseases.
MIR6746 is a 24.1 kilobase (kb) miRNA that contains 207 amino acid (aa) residues. It is expressed in various tissues, including liver, lung, and brain, and has been shown to be involved in the regulation of various gene expression pathways, including cell growth, apoptosis, and inflammation. MIR6746 has also been shown to play a role in the development and progression of certain diseases, such as cancer.
One of the key functions of MIR6746 is its ability to regulate the expression of target genes. MIR6746 has been shown to interact with various target genes, including but not limited to HDACs, sorafenelates, and p53. These interactions cause MIR6746 to alter the target gene's stability, either by increasing or decreasing its expression levels. This regulation of gene expression is critical for the development and progression of various diseases, including cancer.
In addition to its role in gene expression, MIR6746 has also been shown to play a critical role in the regulation of cellular processes that are important for disease development, such as cell apoptosis. MIR6746 has been shown to interact with various cellular signaling pathways, including the TGF-?? pathway. This interaction causes MIR6746 to regulate the expression of genes involved in cell apoptosis, including Bcl-2.
MIR6746's role in cell apoptosis is important for understanding the mechanisms of disease progression and for the development of potential therapeutic strategies. The TGF-?? pathway is a well-established source of regulations for cell apoptosis, and MIR6746's role in this pathway suggests that it may be a useful target for the development of drugs that can inhibit or enhance apoptosis.
Another potential function of MIR6746 is its ability to regulate the expression of genes involved in inflammation. MIR6746 has been shown to interact with various signaling pathways, including the NF-kB pathway. This interaction causes MIR6746 to regulate the expression of genes involved in inflammation, including nuclear factor kappa B.
The role of MIR6746 in inflammation is important for understanding the mechanisms of chronic inflammation and for the development of potential therapeutic strategies. Chronic inflammation has been linked to a number of diseases, including cancer, and MIR6746's role in regulating the expression of genes involved in inflammation suggests that it may be a useful target for the development of drugs that can inhibit or enhance inflammation.
In conclusion, MIR6746 is a unique and highly promising drug target and biomarker due to its ability to regulate gene expression and play a role in the regulation of cellular processes that are important for disease progression. The regulation of gene expression by MIR6746 makes it an attractive target for the development of drugs that can inhibit or enhance apoptosis, inflammation, or other cellular processes that are involved in disease progression. Further research is needed to fully understand the mechanisms of MIR6746's role in disease and to develop effective therapeutic strategies based on its unique properties.
Protein Name: MicroRNA 6746
The "MIR6746 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR6746 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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