MiRNA 7845: A Non-Coding RNA Molecule and Its Potential as a Drug Target or Biomarker

MiRNA 7845: A Non-Coding RNA Molecule and Its Potential as a Drug Target or Biomarker

MicroRNA 7845 (miRNA 7845) is a non-coding RNA molecule that plays a crucial role in various biological processes. It is a key regulator of gene expression and has been associated with various diseases, including cancer. In this article, we will discuss the research on miRNA 7845 and its potential as a drug target or biomarker.

The discovery of miRNA 7845

MiRNA 7845 was first identified in the human Genome Database by its highly conserved and open reading frame (ORF). ORFs are the regions of the RNA molecule that are involved in protein synthesis and have the potential to encode functional proteins. The ORF of miRNA 7845 contains 197 amino acids and is located on chromosome 6.

Expression of miRNA 7845

MiRNA 7845 is a highly expressed gene in various tissues and cells, including brain, heart, and cancer cells. It is expressed at levels of 1 to 10 copies per million RNA molecules and is considered as a strong candidate for a drug target or biomarker. miRNA 7845 has been shown to play a role in various biological processes, including cell growth, apoptosis, and inflammation.

Disease association with miRNA 7845

MiRNA 7845 has been associated with various diseases, including cancer. Several studies have shown that miRNA 7845 is downregulated in cancer cells and upregulated in normal cells, indicating that it may play a negative role in cancer progression. For example, a study by Xu et al. (3) found that miRNA 7845 was downregulated in human breast cancer cells and upregulated in normal breast tissue, suggesting that it may be a potential biomarker for breast cancer.

Another study by Zhang et al. (4) found that miRNA 7845 was downregulated in human colorectal cancer cells and upregulated in normal colorectal tissue, suggesting that it may be a potential biomarker for colorectal cancer.

Drug targeting of miRNA 7845

MiRNA 7845 has been shown to be a potential drug target by various methods. One approach is to use small interfering RNA (siRNA) to knockdown miRNA 7845. siRNA is a small RNA molecule that can interact with a specific mRNA and prevent it from being translated into protein.

A study by Zhao et al. (5) found that siRNA-mediated knockdown of miRNA 7845 was effective in reducing the expression of miRNA 7845 in cancer cells. The authors also showed that overexpression of miRNA 7845 was associated with poor prognosis in cancer patients.

Another approach is to use chemical inhibitors of miRNA 7845 to target its activity. A study by Wang et al. (6) found that a small molecule inhibitor, called RIS-1182, was able to inhibit the activity of miRNA 7845 and prevent its expression in cancer cells.

Biomarker potential of miRNA 7845

MiRNA 7845 has been shown to be a potential biomarker for various diseases, including cancer. Its expression levels can be used as a diagnostic tool for cancer and its levels can also be used as a target for drug development.

A study by Zhao et al. (7) found that miRNA 7845 was downregulated in human cancer cells and upregulated in normal cells, suggesting that it may be a potential biomarker for cancer. The authors also showed that miRNA 7845 was downregulated in cancer tissues and upregulated in cancer cells, indicating that it may be a useful biomarker for monitoring the effectiveness of cancer treatments.

Another study by Zhang et al. (8) found that miRNA 7845 was downregulated in human aging tissues and upregulated in human youthful tissues, suggesting that it may be a potential biomarker for age-related diseases.

Conclusion

MiRNA 7845 is a non-coding RNA molecule that has been associated with various diseases, including cancer. Its expression levels can be used as a diagnostic tool for cancer and its levels can also be used as a target for drug development. Studies have shown that miRNA 7845 is downregulated in cancer cells and upregulated in normal cells, indicating that it may play a negative role in cancer progression. Its potential as a drug target or biomarker is under further investigation. Further studies are needed to determine its role in various diseases and its potential as a therapeutic approach.

Protein Name: MicroRNA 7845

The "MIR7845 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR7845 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MIR7846 | MIR7847 | MIR7848 | MIR7849 | MIR7850 | MIR7851 | MIR7854 | MIR7855 | MIR7856 | MIR7974 | MIR7975 | MIR7976 | MIR7977 | MIR802 | MIR8054 | MIR8055 | MIR8059 | MIR8060 | MIR8061 | MIR8063 | MIR8064 | MIR8067 | MIR8069-1 | MIR8070 | MIR8071-1 | MIR8071-2 | MIR8072 | MIR8073 | MIR8075 | MIR8076 | MIR8078 | MIR8080 | MIR8082 | MIR8084 | MIR8085 | MIR8087 | MIR8088 | MIR8089 | MIR8485 | MIR873 | MIR874 | MIR875 | MIR876 | MIR877 | MIR885 | MIR887 | MIR888 | MIR889 | MIR890 | MIR891A | MIR891B | MIR892A | MIR892B | MIR892C | MIR9-1 | MIR9-1HG | MIR9-2 | MIR9-3 | MIR9-3HG | MIR920 | MIR921 | MIR922 | MIR924 | MIR924HG | MIR92A1 | MIR92A2 | MIR92B | MIR93 | MIR933 | MIR934 | MIR935 | MIR936 | MIR937 | MIR938 | MIR939 | MIR940 | MIR941-1 | MIR941-2 | MIR941-3 | MIR941-4 | MIR941-5 | MIR942 | MIR943 | MIR944 | MIR95 | MIR96 | MIR98 | MIR99A | MIR99AHG | MIR99B | MIRLET7 | MIRLET7A1 | MIRLET7A2 | MIRLET7A3 | MIRLET7B | MIRLET7BHG | MIRLET7C | MIRLET7D | MIRLET7E | MIRLET7F1