LOC105369944: A Drug Target / Disease Biomarker (G105369944)

LOC105369944: A Drug Target / Disease Biomarker

LOC105369944 is a protein that is expressed in various tissues throughout the body. It is a member of the superfamily of uncharacterized intracellular signaling proteins (SISP), which are known for their ability to regulate cellular signaling pathways. LOC105369944 has been identified as a potential drug target (or biomarker) due to its unique structure and the involvement of various cellular signaling pathways.

The protein LOC105369944 is composed of 21 amino acid residues and has a calculated molecular weight of 33.1 kDa. It is expressed in a variety of tissues, including muscle, heart, brain, and liver. LOC105369944 is a cytoplasmic protein and is predominantly localized to the endoplasmic reticulum (ER) and the transmembrane space (TMS).

One of the defining features of LOC105369944 is its unique structure. LOC105369944 has a characteristic Rossmann-fold, which is a type of beta-sheet structure that is composed of a series of parallel beta-strands that give the protein its 3D shape. The Rossmann-fold is a common structural motif that is found in a variety of proteins, including enzymes, toxins, and signaling proteins.

The unique structure of LOC105369944 has led to its potential as a drug target. One of the primary functions of LOC105369944 is to regulate the activity of various signaling pathways, including the TGF-β pathway. The TGF-β pathway is a well-established pathway that plays a central role in the regulation of cellular growth, differentiation, and survival. LOC105369944 has been shown to be involved in the regulation of TGF-β signaling by negatively affecting the activity of the protein FGF17.

In addition to its involvement in TGF-β signaling, LOC105369944 is also involved in the regulation of several other cellular signaling pathways. For example, LOC105369944 has been shown to be involved in the regulation of the PI3K/Akt signaling pathway, which is involved in the regulation of cellular signaling pathways that are important for cellular survival and growth.

The potential drug target status of LOC105369944 is supported by its expression in a variety of tissues and the involvement of various cellular signaling pathways. In addition, the unique structure of LOC105369944 is also consistent with the hypothesis that it may be a protein that can be targeted by small molecules or other therapeutic agents. Further research is needed to determine the full scope of LOC105369944's potential as a drug target and to develop methods for its targeted delivery to specific cell types.

Protein Name: Uncharacterized LOC105369944

The "LOC105369944 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105369944 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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