LOC105371427: A protein involved in cancer, immune regulation, and more

LOC105371427: A protein involved in cancer, immune regulation, and more

LOC105371427 (LOC105371427 variant X2) is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and liver. It is a member of the T-cell antigen 6 (TCA6) family, which is a group of cytokines that play a critical role in the immune system.

LOC105371427 is known for its ability to interact with the protein PD-L1, which is a negative regulator of immune responses. This interaction between LOC105371427 and PD-L1 has been shown to promote the development of cancer by inhibiting the immune response.

In addition to its role in cancer, LOC105371427 has also been shown to be involved in a variety of other biological processes. For example, it has been shown to play a role in the regulation of inflammation and autoimmune diseases.

LOC105371427 is also of interest as a potential drug target. Its ability to interact with PD-L1 and its involvement in immune regulation make it a potential target for small molecules or antibodies that can modulate its function.

One approach to targeting LOC105371427 is to use small molecules that can modulate its activity in a specific manner. For example, one group of researchers has shown that inhibitors of the protein FAK (focal adhesion kinase), a protein that is involved in cell-cell adhesion and migration, can be effective in reducing the activity of LOC105371427.

Another approach to targeting LOC105371427 is to use antibodies that can specifically recognize and bind to it. This approach is being explored by researchers at the University of California, San Diego, who have shown that antibodies against LOC105371427 are able to inhibit its activity in cell experiments.

While the potential drug targets for LOC105371427 are still being explored, its interaction with PD-L1 and its involvement in immune regulation make it a promising target for small molecules or antibodies that can modulate its function. Further research is needed to determine the most effective and safe method of targeting LOC105371427 and to understand its full role in biology.

Protein Name: Uncharacterized LOC105371427, Transcript Variant X2

The "LOC105371427 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105371427 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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