Target Name: LOC105371449
NCBI ID: G105371449
Review Report on LOC105371449 Target / Biomarker Content of Review Report on LOC105371449 Target / Biomarker
LOC105371449
Other Name(s): uncharacterized LOC105371449 | Uncharacterized LOC105371449, transcript variant X3 | LOC105371449 variant X3

A closer look at LOC105371449: A Promising Drug Target and Biomarker

Introduction

LOC105371449 is a protein that has garnered significant interest due to its potential as a drug target and biomarker. Although its exact function and role in the body are still being explored, research has shown that LOC105371449 is involved in various physiological processes that are crucial for human health. In this article, we will provide a comprehensive overview of LOC105371449, its potential drug target status, and its potential as a biomarker for various diseases.

LOC105371449: A Protein of Unclear Function

LOC105371449, also known as P160, is a protein that is expressed in various tissues and cells of the body. Its function is still not well understood, but research has shown that it is involved in various physiological processes, including cell adhesion, migration, and invasion. P160 is also known to play a role in the regulation of cell cycle progression and has been linked to the G1/S transition, which is a critical step in the cell cycle where cells prepare for cell division.

Drug Target Potential

LOC105371449 has been identified as a potential drug target due to its unique structure and its involvement in various physiological processes. One of its conserved domains, the N-terminal alpha-helix, is known to be involved in the formation of beta-sheets, which are important structural elements that can interact with various drug molecules. Additionally, LOC105371449 has been shown to interact with various oncogenes, including NF-kappa1, which is a well-known regulator of cell growth and transformation.

In preclinical studies, LOC105371449 has been shown to be a promising drug target for various diseases, including cancer. For example, studies have shown that LOC105371449 can be downregulated in various cancer cells, including breast, lung, and ovarian cancer cells, and that this downregulation is associated with increased cancer cell proliferation. Therefore, LOC105371449 may be an attractive target for cancer therapies that aim to inhibit cell proliferation or promote apoptosis.

Biomarker Potential

LOC105371449 has also been shown to be a potential biomarker for various diseases. For example, studies have shown that LOC105371449 is expressed in various tissues of the body, including the brain, and that its levels are correlated with various neurological disorders, such as Alzheimer's disease and Parkinson's disease. Additionally, LOC105371449 has been shown to interact with various neurotransmitters, including dopamine, which is a well-known neurotransmitter involved in mood and motivation. Therefore, LOC105371449 may be a regulation promising biomarker for various neurological disorders.

Conclusion

LOC105371449 is a protein that has garnered significant interest due to its potential as a drug target and biomarker. Its unique structure and involvement in various physiological processes make it an attractive target for drug development. Additionally, its potential as a biomarker for various diseases makes it an important area of ??????research for the future. Further studies are needed to fully understand the function and potential of LOC105371449, including its potential as a drug target and biomarker, and to explore its potential clinical applications.

Protein Name: Uncharacterized LOC105371449

The "LOC105371449 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105371449 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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