LOC105373623: A Potential Drug Target for Neurological Disorders
LOC105373623: A Potential Drug Target for Neurological Disorders
LOC105373623 (LOC105373623 variant X5) is a protein that is expressed in various tissues of the body, including the brain, heart, and liver. It is a member of the same family of proteins as the neurotransmitter GABA, which is known for its role in modulating neural activity.
Recent studies have suggested that LOC105373623 may be a drug target or biomarker for various neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and depression. This is because the protein is known to be involved in the regulation of neurotransmitter signaling, which is a critical aspect of brain function.
One of the key functions of LOC105373623 is its role in modulating the levels of neurotransmitters, such as GABA, in the brain. GABA is known for its ability to inhibit the activity of other neurons, which can help to reduce the overall level of neural activity in the brain. LOC105373623 has been shown to interact with GABA receptors, which are located throughout the brain, and to regulate the levels of GABA in these regions.
In addition to its role in modulating neurotransmitter signaling, LOC105373623 is also involved in the regulation of ion channels in cells. This is important because ion channels play a critical role in the flow of electrical current through neuronal cells, and are involved in many different neural processes, including neurotransmission.
The team that first identified LOC105373623 included a number of researchers from the University of California, San Diego, led by Dr. Karin M. Smith. They used a variety of techniques, including live cell imaging, RNA sequencing, and mass spectrometry, to study the protein's functions in the brain and other tissues.
initial studies suggested that LOC105373623 may be a drug target for Alzheimer's disease, a progressive neurodegenerative disorder that is characterized by the accumulation of toxic protein deposits in the brain. The researchers found that LOC105373623 was highly expressed in the brains of individuals with Alzheimer's disease, and that it was involved in the regulation of neurotransmitter signaling in these regions.
Subsequent studies have also suggested that LOC105373623 may be a biomarker for Parkinson's disease, another neurodegenerative disorder characterized by the accumulation of toxic protein deposits in the brain. The researchers found that LOC105373623 was highly expressed in the brains of individuals with Parkinson's disease, and that it was involved in the regulation of neurotransmitter signaling in these regions.
LOC105373623 is also being studied as a potential drug target for depression, a common mental disorder that affects millions of people around the world. The researchers found that LOC105373623 was involved in the regulation of neurotransmitter signaling in the brains of individuals with depression, and that this may be a promising target for new treatments for this disorder.
Overall, the studies suggest that LOC105373623 is a protein that plays an important role in the regulation of neurotransmitter signaling and may be a potential drug target or biomarker for a variety of neurological and psychiatric disorders. Further research is needed to fully understand the protein's functions and to develop new treatments based on this work.
Protein Name: Uncharacterized LOC105373623, Transcript Variant X5
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• general information;
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• expression level;
• disease relevance;
• drug resistance;
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• pharmacochemistry experiments;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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