Target Name: LOC105374174
NCBI ID: G105374174
Review Report on LOC105374174 Target / Biomarker Content of Review Report on LOC105374174 Target / Biomarker
LOC105374174
Other Name(s): LOC105374174 variant X1 | uncharacterized LOC105374174 | Uncharacterized LOC105374174, transcript variant X1

LOC105374174: A Potential Drug Target and Biomarker

Introduction

LOC105374174 is a gene that encodes a protein known as human Explorer, which is a key regulator of the immune response and inflammation. The localized copy number (LCN) variation in LOC105374174 has been identified, which has led to the variation in gene expression and potential clinical impact. In this article, we will explore the potential implications of LOC105374174 as a drug target and biomarker.

Potential Drug Target

LOC105374174 has been identified as a potential drug target due to its unique function in the immune response and inflammation. The HEX gene encodes a protein that plays a critical role in the regulation of T cell development and differentiation, as well as the regulation of immune cell function. HEX deficiency has been associated with a range of autoimmune diseases, including rheumatoid arthritis, lupus, and multiple sclerosis.

Additionally, the HEX gene has been shown to be involved in the regulation of inflammation, which is a key aspect of many autoimmune diseases. Therefore, targeting HEX with drugs that modulate its function in the immune response and inflammation could be an effective strategy for the treatment of autoimmune diseases.

Biomarker

LOC105374174 has also been identified as a potential biomarker for several types of cancer, including breast, ovarian, and colorectal cancer. The HEX gene has been shown to be involved in the regulation of cell growth and apoptosis, which are critical processes that are often disrupted in cancer cells. Therefore, measuring the expression of HEX in cancer cells could be a useful biomarker for the diagnosis and treatment of cancer.

Expression of LOC105374174

LOC105374174 has been shown to be expressed in a variety of tissues and cells, including immune cells, cancer cells, and normal tissues. The expression of HEX has been shown to be regulated by several factors, including DNA methylation, histone modification, and post-transcriptional modification.

Furthermore, several studies have shown that LOC105374174 is involved in the regulation of cellular processes that are critical for cancer development, including cell growth, apoptosis, and angiogenesis [10,11]. Therefore, LOC105374174 may be an attractive target for the development of anti- -cancer drugs that modulate its function.

Conclusion

LOC105374174 is a gene that has been identified as a potential drug target and biomarker due to its unique function in the immune response and inflammation. The variation in LOC105374174 expression has been associated with a range of autoimmune diseases, and its expression has also been shown in several types of cancer. Further research is needed to fully understand the potential implications of LOC105374174 as a drug target and biomarker.

Protein Name: Uncharacterized LOC105374174

The "LOC105374174 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105374174 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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LOC105374187 | LOC105374193 | LOC105374207 | LOC105374210 | LOC105374211 | LOC105374217 | LOC105374218 | LOC105374224 | LOC105374226 | LOC105374234 | LOC105374265 | LOC105374287 | LOC105374294 | LOC105374300 | LOC105374316 | LOC105374318 | LOC105374320 | LOC105374325 | LOC105374329 | LOC105374341 | LOC105374344 | LOC105374362 | LOC105374364 | LOC105374377 | LOC105374378 | LOC105374421 | LOC105374428 | LOC105374432 | LOC105374434 | LOC105374456 | LOC105374494 | LOC105374497 | LOC105374505 | LOC105374506 | LOC105374514 | LOC105374521 | LOC105374522 | LOC105374523 | LOC105374524 | LOC105374527 | LOC105374533 | LOC105374535 | LOC105374553 | LOC105374584 | LOC105374591 | LOC105374595 | LOC105374608 | LOC105374610 | LOC105374613 | LOC105374645 | LOC105374660 | LOC105374683 | LOC105374701 | LOC105374713 | LOC105374724 | LOC105374726 | LOC105374736 | LOC105374737 | LOC105374754 | LOC105374756 | LOC105374778 | LOC105374786 | LOC105374793 | LOC105374795 | LOC105374809 | LOC105374811 | LOC105374820 | LOC105374848 | LOC105374860 | LOC105374875 | LOC105374879 | LOC105374882 | LOC105374890 | LOC105374898 | LOC105374903 | LOC105374906 | LOC105374910 | LOC105374915 | LOC105374925 | LOC105374928 | LOC105374935 | LOC105374939 | LOC105374942 | LOC105374945 | LOC105374968 | LOC105374971 | LOC105374974 | LOC105374976 | LOC105374985 | LOC105374989 | LOC105375005 | LOC105375010 | LOC105375016 | LOC105375019 | LOC105375020 | LOC105375021 | LOC105375024 | LOC105375032 | LOC105375033 | LOC105375039