LOC105377590: A Potential Drug Target and Biomarker (G105377590)

LOC105377590: A Potential Drug Target and Biomarker

LOC105377590 is a protein that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. Its unique structure and function make it an intriguing candidate for further research and development.

The protein LOC105377590 is a member of the superfamily of evolutionarily conserved transmembrane proteins, known as the TRP/PML family. This family is characterized by the presence of a protein that contains a nucleotide-binding oligomerization domain (NBD), a protein-coding domain , and a C-terminal transmembrane domain. LOC105377590 is characterized by a unique NBD that is composed of a nucleotide-binding domain and a leucine-rich domain.

LOC105377590 functions as a negative regulator of the nuclear export pathway, which is responsible for the export of proteins from the nucleus to the cytoplasm. The NBD in LOC105377590 plays a critical role in the regulation of this pathway by binding to specific target proteins and preventing their export from the nucleus.

The NBD in LOC105377590 has been shown to interact with various protein partners, including the nuclear export protein Nup80. This interaction between the protein and its partner suggests that LOC105377590 may be a useful target for drugs that are designed to modulate the activity of Nup80 and other export proteins.

In addition to its potential as a drug target, LOC105377590 has also been identified as a potential biomarker for various diseases. The expression of LOC105377590 has been shown to be elevated in a variety of cancer samples, including breast, ovarian, and colorectal cancers. This increase in expression levels suggests that LOC105377590 may be a useful biomarker for cancer diagnosis and treatment.

Furthermore, LOC105377590 has also been shown to be involved in the regulation of cellular processes that are important for maintaining tissue homeostasis, including cell adhesion, migration, and invasion. This involvement in these processes suggests that LOC105377590 may be a useful target for drugs that are designed to modulate the activity of cell adhesion molecules, such as cadherins and integrins.

In conclusion, LOC105377590 is a protein that has the potential to be a drug target and biomarker for various diseases. Its unique structure and function make it an intriguing candidate for further research and development. Further studies are needed to determine the full extent of LOC105377590's potential as a drug and biomarker, and to explore the most effective and safe ways to target or use this protein for therapeutic purposes.

Protein Name: Uncharacterized LOC105377590

The "LOC105377590 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105377590 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

LOC105377596 | LOC105377621 | LOC105377632 | LOC105377641 | LOC105377642 | LOC105377643 | LOC105377646 | LOC105377662 | LOC105377666 | LOC105377683 | LOC105377699 | LOC105377700 | LOC105377714 | LOC105377715 | LOC105377721 | LOC105377727 | LOC105377730 | LOC105377732 | LOC105377739 | LOC105377778 | LOC105377785 | LOC105377795 | LOC105377806 | LOC105377809 | LOC105377824 | LOC105377844 | LOC105377845 | LOC105377858 | LOC105377862 | LOC105377864 | LOC105377865 | LOC105377871 | LOC105377876 | LOC105377877 | LOC105377882 | LOC105377891 | LOC105377913 | LOC105377920 | LOC105377923 | LOC105377924 | LOC105377927 | LOC105377941 | LOC105377968 | LOC105377979 | LOC105377981 | LOC105377989 | LOC105378009 | LOC105378010 | LOC105378011 | LOC105378019 | LOC105378022 | LOC105378058 | LOC105378066 | LOC105378072 | LOC105378082 | LOC105378085 | LOC105378088 | LOC105378091 | LOC105378099 | LOC105378105 | LOC105378110 | LOC105378120 | LOC105378145 | LOC105378146 | LOC105378150 | LOC105378178 | LOC105378189 | LOC105378204 | LOC105378206 | LOC105378228 | LOC105378305 | LOC105378310 | LOC105378314 | LOC105378316 | LOC105378318 | LOC105378327 | LOC105378334 | LOC105378335 | LOC105378339 | LOC105378340 | LOC105378342 | LOC105378347 | LOC105378409 | LOC105378414 | LOC105378460 | LOC105378477 | LOC105378486 | LOC105378492 | LOC105378502 | LOC105378508 | LOC105378515 | LOC105378517 | LOC105378520 | LOC105378525 | LOC105378526 | LOC105378537 | LOC105378543 | LOC105378559 | LOC105378560 | LOC105378586