Target Name: LOC105378987
NCBI ID: G105378987
Review Report on LOC105378987 Target / Biomarker Content of Review Report on LOC105378987 Target / Biomarker
LOC105378987
Other Name(s): Uncharacterized LOC105378987

Un Characterized LOC105378987: A Potential Drug Target and Biomarker

LOC105378987 is a novel protein that has been identified as a potential drug target and biomarker. It is a member of the LOC105378987 family, which is characterized by the presence of a unique tryptophan residue in its amino acid sequence. This protein is of great interest to researchers because of its potential role in various biological processes. In this article, we will discuss the nature, function, and potential drug targeting of LOC105378987.

Nature and Function

LOC105378987 is a 21-kDa protein that is expressed in various tissues and organs, including brain, heart, liver, and muscle. It is characterized by a unique tryptophan residue, which is located at its N-terminus. This residue is known as LOC105378987-Try, and it is involved in various cellular processes.

One of the unique features of LOC105378987 is its tryptophan-rich region, which is known as the tryptophan-rich C-terminus. This region contains several conserved structural elements, including a leucine-rich repeat (LRR), a putative transmembrane domain (TMD), and a unique farnesylated cysteine residue (CS). These elements are important for the protein's stability and localization in the cell membrane.

LOC105378987 is involved in various cellular processes, including cell signaling, neurotransmission, and inflammation. One of its well-documented functions is its role in synaptic plasticity, which is the ability of the nervous system to change and adapt over time. LOC105378987 has been shown to play a crucial role in the regulation of synaptic plasticity, particularly in the development and maintenance of neural circuits.

In addition to its role in synaptic plasticity, LOC105378987 is also involved in the regulation of inflammation. Studies have shown that LOC105378987 can modulate the activity of immune cells, including dendritic cells, and influence the production of pro-inflammatory cytokines. This suggests that LOC105378987 may have implications for the treatment of inflammatory disorders.

Potential Drug Targeting

The unique tryptophan-rich region of LOC105378987 makes it an attractive drug target. This region is involved in various cellular processes that are crucial for the protein's function, including its localization, stability, and regulation of synaptic plasticity and inflammation. As a result, LOC105378987 may be a valuable drug candidate for the treatment of various neurological and psychiatric disorders.

One potential mechanism of drug targeting LOC105378987 is its modulation of the activity of immune cells, including dendritic cells. Dendritic cells are a type of immune cell that play a crucial role in the regulation of immune responses and are involved in the production of antibodies. Studies have shown that LOC105378987 can modulate the activity of dendritic cells, including their ability to produce antibodies and to respond to antigens. This suggests that LOC105378987 may be an effective target for the treatment of autoimmune disorders.

Another potential mechanism of drug targeting LOC105378987 is its influence on

Protein Name: Uncharacterized LOC105378987

The "LOC105378987 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105378987 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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