Target Name: LOC114224
NCBI ID: G114224
Review Report on LOC114224 Target / Biomarker Content of Review Report on LOC114224 Target / Biomarker
LOC114224
Other Name(s): PRO2852 | uncharacterized LOC114224 | Uncharacterized LOC114224

LOC114224: A Multi-Functional Ankyrin Gene Protein

LOC114224 (PRO2852) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the evolutionarily conserved family of transmembrane proteins known as the ankyrin gene family. LOC114224 is unique due to its unique function and its presence in several critical organs of the body.

One of the most significant functions of LOC114224 is its role in the regulation of ion channels. These channels are responsible for the flow of electrical signals through the cell membrane, and they play a crucial role in various physiological processes, including muscle contractions, nerve signals , and brain function. LOC114224 helps to regulate the activity of these channels, ensuring that they remain in optimal function and help to maintain the integrity of the cell membrane.

Another important function of LOC114224 is its role in cell signaling. LOC114224 can interact with various signaling molecules, including insulin, to regulate cellular processes such as metabolism, inflammation, and stress. This interaction between LOC114224 and insulin highlights the protein's role in the regulation of glucose levels, which is critical for maintaining brain function and overall health.

LOC114224 is also involved in the regulation of pain perception. Studies have shown that LOC114224 is involved in the transmission of pain signals from the body to the brain. This protein has been shown to interact with other proteins involved in pain signaling, including the neurotransmitter N -methyl-D-aspartate (NMDA). This interaction between LOC114224 and NMDA highlights the protein's role in the regulation of pain perception and the potential for LOC114224 to be targeted as a drug or biomarker for pain management.

In addition to its role in cell signaling and pain perception, LOC114224 is also involved in the regulation of inflammation. This protein has been shown to interact with various cytokines, including TNF-alpha, a potent regulator of inflammation. This interaction between LOC114224 and TNF -alpha highlights the protein's role in the regulation of inflammatory responses and the potential for LOC114224 to be targeted as an anti-inflammatory drug.

The ankyrin gene family is known for its unique structure and its ability to generate a variety of unique proteins with distinct functions. LOC114224 is no exception. This protein has a unique structure that allows it to interact with a wide range of molecules, including ions, signaling molecules, and cytokines. This unique structure also allows LOC114224 to be targeted as a drug or biomarker for a wide range of diseases, including neurodegenerative disorders, pain management, and inflammatory diseases.

In conclusion, LOC114224 (PRO2852) is a unique and highly functionally diverse protein that plays a critical role in the regulation of ion channels, cell signaling, pain perception, and inflammation. Its unique structure and its ability to interact with a wide range of molecules make it an attractive target for drug development and biomarker research. Further studies are needed to fully understand the functions of LOC114224 and its potential as a drug or biomarker.

Protein Name: Uncharacterized LOC114224

The "LOC114224 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC114224 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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