RPS15P2: A Promising Drug Target / Biomarker (G100271066)

Target Name: RPS15P2

NCBI ID: G100271066

RPS15P2

Other Name(s): RPS15_1_177 | Ribosomal protein S15 pseudogene 2 | ribosomal protein S15 pseudogene 2

RPS15P2: A Promising Drug Target / Biomarker

The protein RPS15P2 is a key regulator of the Replication-Ready Pool (RPS) in eukaryotic cells. The RPS is a complex protein that forms the basis of the replication of DNA in eukaryotic cells. It is composed of several subunits, including RPS15, RPS16, RPS17, and RPS18. RPS15P2 is one of the subunits of RPS and is involved in the regulation of DNA replication.

The RPS is a critical component of the replication machinery and plays a vital role in the maintenance of genetic accuracy in eukaryotic cells. It ensures that the DNA double helix is replicated accurately and that any errors or mutations are repaired. RPS15P2 is specifically involved in the regulation of the RPS replication complex.

Drug Target and Biomarker

RPS15P2 is a drug target of interest because of its involvement in the regulation of DNA replication. Several studies have identified potential drug targets for RPS15P2 and have shown that inhibiting its activity can lead to defects in DNA replication. These studies have led to the development of new treatments for various diseases, including cancer, neurodegenerative diseases, and genetic disorders.

One of the potential drug targets for RPS15P2 is inhibiting its activity with small molecules. Small molecules have been shown to be effective in inhibiting RPS15P2 activity and have been used in clinical trials to treat various diseases. For example, a small molecule called U-8719 has been shown to inhibit the activity of RPS15P2 and has been used in clinical trials to treat neurodegenerative diseases.

Another potential drug target for RPS15P2 is its interaction with other proteins. RPS15P2 has been shown to interact with several other proteins, including the protein Rb1. Rb1 is a key regulator of the DNA replication complex and has been shown to interact with RPS15P2 to regulate DNA replication. Therefore, targeting Rb1 with small molecules may also be an effective way to inhibit RPS15P2 activity.

Biomarker

RPS15P2 is also a potential biomarker for several diseases. Its involvement in the regulation of DNA replication makes it an attractive target for diagnostic tests for diseases that affect DNA replication. For example, RPS15P2 has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Therefore, measuring the level of RPS15P2 activity in brain tissue may be an effective way to diagnose these diseases.

In addition, RPS15P2 has also been shown to be involved in the development of cancer. Its involvement in the regulation of DNA replication makes it an attractive target for cancer therapies that target DNA replication. For example, inhibiting RPS15P2 activity with small molecules has been shown to be effective in treating various cancers, including breast cancer and colorectal cancer.

Conclusion

RPS15P2 is a protein that plays a critical role in the regulation of DNA replication in eukaryotic cells. Its involvement in the replication machinery makes it an attractive target for drug development and diagnostic tests. The development of new treatments for various diseases based on RPS15P2 inhibition is an exciting area of research with great potential.

Protein Name: Ribosomal Protein S15 Pseudogene 2

The "RPS15P2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RPS15P2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets