Target Name: CMPK2
NCBI ID: G129607
Review Report on CMPK2 Target / Biomarker Content of Review Report on CMPK2 Target / Biomarker
CMPK2
Other Name(s): OTTHUMP00000200305 | TYKi | UMP-CMP kinase 2, mitochondrial (isoform 1) | Thymidine monophosphate kinase 2 | Mitochondrial UMP-CMP kinase | Thymidylate kinase family LPS-inducible member | thymidine monophosphate kinase 2 | NDK | UMP/CMP kinase | UMP-CMP kinase 2, mitochondrial | CMPK2_HUMAN | cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial | Cytidine/uridine monophosphate kinase 2, transcript variant 1 | nucleoside-diphosphate kinase | Nucleoside-diphosphate kinase | cytidine/uridine monophosphate kinase 2 | TMPK2 | UMP-CMPK2 | CMPK2 variant 1 | thymidylate kinase family LPS-inducible member | mitochondrial UMP-CMP kinase | Cytidylate kinase 2 | cytidylate kinase 2

CMPK2: A Protein Involved in Cell Signaling Pathways

CMPK2, also known as OTHUMP00000200305, is a protein that is expressed in almost all human tissues and plays a critical role in cell signaling pathways. It is a key regulator of the PI3K/Akt signaling pathway, which is involved in many cellular processes including cell survival, angiogenesis, and inflammation.

The PI3K/Akt signaling pathway is a well-established target for many drugs, including anti-cancer drugs, anti-inflammatory drugs, and blood pressure drugs. The pathway is involved in the regulation of many different proteins, including many cytoskeletal proteins, neurotransmitters, and enzymes involved in cell signaling.

CMPK2 is a key regulator of the PI3K/Akt signaling pathway. It is a 21-kDa protein that is expressed in almost all human tissues. It plays a critical role in the regulation of cellular processes, including cell survival, angiogenesis, and inflammation.

CMPK2 is involved in the regulation of many different cellular processes. For example, it is involved in the regulation of cell adhesion, which is critical for the development and maintenance of tissues and organs. It is also involved in the regulation of cell migration, which is critical for the formation of tissues and organs during development.

CMPK2 is also involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed. It is a key regulator of the production and function of endothelial cells, which are responsible for the formation of blood vessels.

CMPK2 is also involved in the regulation of inflammation. It is a key regulator of the production and function of immune cells, which play a critical role in defending against infection and disease.

CMPK2 is a drug target that has been targeted by many pharmaceutical companies for the development of new drugs. For example, several companies have developed drugs that target CMPK2 in order to treat a variety of diseases, including cancer, cardiovascular disease, and neurodegenerative diseases.

In addition to its involvement in drug development, CMPK2 is also a potential biomarker for several diseases. For example, it is often used as a biomarker for the diagnosis and prognosis of cancer, as it has been shown to be highly expressed in many types of cancer. It is also used as a biomarker for several cardiovascular diseases, including heart failure and stroke.

CMPK2 is also a potential target for new therapies for treating addiction. Studies have shown that CMPK2 is involved in the regulation of dopamine release, which is a key contributor to the rewarding effects of drugs. Therefore, CMPK2 may be a useful target for the development of new drugs that can treat addiction.

In conclusion, CMPK2 is a protein that is involved in the regulation of many cellular processes, including cell signaling pathways. It is a key regulator of the PI3K/Akt signaling pathway and has been shown to play a critical role in the regulation of cellular processes, including cell survival, angiogenesis, and inflammation. As a result, CMPK2 is a potential drug target and a potential biomarker for several diseases. Further research is needed to fully understand the role of CMPK2 in cell signaling pathways and its potential as a drug target and biomarker.

Protein Name: Cytidine/uridine Monophosphate Kinase 2

Functions: May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs. Also displays broad nucleoside diphosphate kinase activity

The "CMPK2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CMPK2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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