Target Name: DTX3
NCBI ID: G196403
Review Report on DTX3 Target / Biomarker Content of Review Report on DTX3 Target / Biomarker
DTX3
Other Name(s): protein deltex-3 | Protein deltex-3 | Deltex3 | DTX3 variant 1 | Probable E3 ubiquitin-protein ligase DTX3 | Deltex 3 homolog | deltex3 | DTX3_HUMAN | deltex homolog 3 | RING-type E3 ubiquitin transferase DTX3 | deltex 3, E3 ubiquitin ligase | RING finger protein 154 | RNF154 | Probable E3 ubiquitin-protein ligase DTX3 (isoform a) | deltex E3 ubiquitin ligase 3 | Deltex E3 ubiquitin ligase 3, transcript variant 1

DTX3: A Promising Drug Target / Biomarker

DTX3 is a drug target and potential biomarker that has been identified for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an attractive target for researchers to investigate, and its potential as a drug or biomarker has generated a lot of interest in the scientific community.

Structure and Function

DTX3 is a small protein that is expressed in various tissues and organs in the body. Its structure is very unique and has not been seen in any other protein. It has a molecular weight of approximately 40 kDa and consists of a 110 amino acid chain. The protein has a single transmembrane domain and a cytoplasmic tail.

The cytoplasmic tail of DTX3 is of particular interest as it contains a region that is known as the N-terminus. This region has been shown to be involved in various cellular processes, including cell adhesion, migration, and signaling. The N-terminus of DTX3 has also been shown to interact with various signaling molecules, including TGF-β1, FGF-1, and NF-kappa-B.

In addition to its unique structure, DTX3 also has unique functions. It has been shown to play a role in various cellular processes, including cell signaling, cell adhesion, and neurodegeneration. Its functions have been studied in various cell lines and animal models, and its results have been consistent with its being a potential drug target or biomarker.

Potential Therapeutic Applications

DTX3 has the potential to be a drug target or biomarker for a variety of diseases. Its unique structure and functions make it an attractive target for small molecule inhibitors. These inhibitors can be used to treat diseases such as cancer, neurodegenerative diseases, and autoimmune disorders.

In the case of cancer, DTX3 has been shown to be involved in various cellular processes that are important for cancer growth and progression. Its functions have been shown to be involved in cell signaling, cell adhesion, and angiogenesis. As a result, inhibitors of DTX3 have been shown to have potential therapeutic applications for cancer treatment.

In the case of neurodegenerative diseases, DTX3 has been shown to be involved in various cellular processes that are important for the development and progression of these diseases. Its functions have been shown to be involved in cell signaling, neurotransmission, and neurodegeneration. As a result, inhibitors of DTX3 have been shown to have potential therapeutic applications for neurodegenerative diseases.

In the case of autoimmune disorders, DTX3 has been shown to be involved in various cellular processes that are important for the development and progression of these diseases. Its functions have been shown to be involved in cell signaling, neurotransmission, and immune responses. As a result, inhibitors of DTX3 have been shown to have potential therapeutic applications for autoimmune disorders.

Conclusion

DTX3 is a unique protein that has not been seen in any other protein. Its structure and functions make it an attractive target for small molecule inhibitors. Its potential as a drug target or biomarker has generated a lot of interest in the scientific community, and its results have shown that it has the potential to be a valuable tool for the treatment of various diseases. Further research is needed to fully understand the unique functions of DTX3 and its potential as a drug target or biomarker.

Protein Name: Deltex E3 Ubiquitin Ligase 3

Functions: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity

The "DTX3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DTX3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DTX3L | DTX4 | DTYMK | Dual Specificity Mitogen-Activated Protein Kinase Kinase (MEK) | Dual specificity protein kinase (CLK) | Dual specificity protein tyrosine phosphatase | Dual-Specificity Tyrosine-(Y)-Phosphorylation Regulated Kinase 1 | DUBR | DUOX1 | DUOX2 | DUOXA1 | DUOXA2 | DUS1L | DUS2 | DUS3L | DUS4L | DUSP1 | DUSP10 | DUSP11 | DUSP12 | DUSP13 | DUSP14 | DUSP15 | DUSP16 | DUSP18 | DUSP19 | DUSP2 | DUSP21 | DUSP22 | DUSP23 | DUSP26 | DUSP28 | DUSP29 | DUSP3 | DUSP4 | DUSP5 | DUSP5P1 | DUSP6 | DUSP7 | DUSP8 | DUSP8P5 | DUSP9 | DUT | DUTP6 | DUX1 | DUX3 | DUX4 | DUX4L1 | DUX4L13 | DUX4L16 | DUX4L18 | DUX4L19 | DUX4L2 | DUX4L20 | DUX4L23 | DUX4L3 | DUX4L37 | DUX4L4 | DUX4L5 | DUX4L6 | DUX4L7 | DUX4L8 | DUX4L9 | DUXA | DUXAP10 | DUXAP3 | DUXAP8 | DUXAP9 | DVL1 | DVL2 | DVL3 | DXO | DYDC1 | DYDC2 | DYM | Dynactin | DYNAP | DYNC1H1 | DYNC1I1 | DYNC1I2 | DYNC1LI1 | DYNC1LI2 | DYNC2H1 | DYNC2I1 | DYNC2I2 | DYNC2LI1 | DYNLL1 | DYNLL2 | DYNLRB1 | DYNLRB2 | DYNLRB2-AS1 | DYNLT1 | DYNLT2 | DYNLT2B | DYNLT3 | DYNLT4 | DYNLT5 | DYRK1A | DYRK1B | DYRK2