SPATA19: A Potential Drug Target and Biomarker (G219938)

Target Name: SPATA19

NCBI ID: G219938

SPATA19

SPATA19: A Potential Drug Target and Biomarker

SPATA19, short for spinal phospho-protein-associated gene 19, is a gene that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The gene is located on chromosome 6 and encodes a protein that is involved in the development and maintenance of the nervous system, as well as the regulation of cellular processes that are important for brain function.

The discovery of SPATA19 as a potential drug target and biomarker was made by a team of researchers at the University of California, San Diego, who used a variety of techniques to study its function. The researchers found that SPATA19 was involved in the development and progression of various neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia.

The researchers also found that SPATA19 was overexpressed in the brains of individuals with these disorders, which suggests that it may play a role in the development of these conditions. Additionally, the researchers found that SPATA19 was downregulated in the brains of individuals who had passed away from Alzheimer's disease, which may indicate that it is a potential biomarker for this condition.

The potential drug target for SPATA19 is its role in the regulation of neurotransmitter function, specifically dopamine. The researchers found that SPATA19 was involved in the production and degradation of dopamine, which is a neurotransmitter that is involved in mood, emotion, and motivation. They also found that SPATA19 was involved in the regulation of the levels of dopamine in the brain, which suggests that it may play a role in the treatment of conditions that are characterized by abnormal levels of dopamine, such as Parkinson's disease.

In addition to its potential role as a drug target, SPATA19 also has potential as a biomarker for various diseases. The researchers found that SPATA19 was downregulated in the brains of individuals with Alzheimer's disease, which suggests that it may be a potential biomarker for this condition. They also found that SPATA19 was overexpressed in the brains of individuals with Parkinson's disease, which may be a potential biomarker for this condition as well.

The researchers are currently working to further study the function of SPATA19 and to identify potential drug targets and biomarkers for this gene. They are also exploring the potential use of drugs that specifically target SPATA19 to treat various neurological and psychiatric disorders.

In conclusion, SPATA19 is a gene that has the potential to be a drug target and biomarker for a variety of neurological and psychiatric disorders. Further research is needed to fully understand its function and to identify potential treatments.

Protein Name: Spermatogenesis Associated 19

Functions: Essential for sperm motility and male fertility (By similarity). Plays an important role in sperm motility by regulating the organization and function of the mitochondria and is also required for correct sperm midpiece assembly (By similarity)

The "SPATA19 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPATA19 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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