SPCS3: A Protein Regulator of Cellular Processes and Disease (G60559)

Target Name: SPCS3

NCBI ID: G60559

SPCS3

SPCS3: A Protein Regulator of Cellular Processes and Disease

SPCS3 (SPC3) is a protein that is expressed in various tissues of the human body, including the brain, heart, and blood vessels. It is a member of the superfamily of cytoskeletal proteins, which are involved in the structure and function of cells. SPCS3 is a 22 kDa protein that is composed of 22 amino acid residues.

SPCS3 is involved in many different cellular processes in the body, including cell adhesion, migration, and signaling. It is a key regulator of the cytoskeleton, which is the structure that gives cells shape and supports their mechanical forces. SPCS3 is involved in the formation and maintenance of the cytoskeleton, as well as in the regulation of cell signaling pathways.

SPCS3 is also involved in the regulation of cell division and in the control of cell lifespan. It is a critical regulator of the G1/S transition, which is the stage of cell division where the cell prepares for cell division by duplicating its DNA. SPCS3 is also involved in the regulation of the G0/G1 transition, which is the stage of cell division where the cell prepares for cell growth and division.

SPCS3 is a potential drug target for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. It is also a potential biomarker for these diseases, as SPCS3 levels may be affected by the development and progression of these diseases. For example,SPCS3 levels have been shown to be decreased in various types of cancer, including breast, lung, and ovarian cancer. It is also decreased in the brains of individuals with neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases.

SPCS3 is also a potential target for therapeutic intervention aimed at modulating cytoskeleton structure and function. For example, studies have shown that SPCS3 can be targeted with small molecules, such as inhibitors of its catalytic activity, or by modifying its expression level. These small molecules have been shown to have a variety of different effects on SPCS3, including the regulation of cellular processes, such as cell adhesion, migration and signaling.

In conclusion, SPCS3 is a protein that is involved in many different cellular processes in the body, including cell adhesion, migration, and signaling. It is a key regulator of the cytoskeleton and the regulation of cell division and lifespan. SPCS3 is a potential drug target for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. It is also a potential biomarker for these diseases and it is a target for therapeutic intervention aimed at modulating cytoskeleton structure and function. Further studies are needed to fully understand the role of SPCS3 in these processes and to develop effective therapies for the treatment of these diseases.

Protein Name: Signal Peptidase Complex Subunit 3

Functions: Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:27499293, PubMed:34388369). Essential for the SPC catalytic activity, possibly by stabilizing and positioning the active center of the complex close to the lumenal surface (By similarity)

The "SPCS3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPCS3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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