SPART: Key Protein Implicated in Disease Development (G23111)

Target Name: SPART

NCBI ID: G23111

SPART

SPART: Key Protein Implicated in Disease Development

SPART (SPG20) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key component of the cytoskeleton, which is the structure that gives cells their shape and supports their growth and movement. SPART is also involved in several cellular processes that are important for cell survival and function, including the regulation of cell division, the development and maintenance of tissues, and the regulation of the blood supply.

SPART has also been shown to play a key role in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. It is often used as a potential drug target or biomarker because of its involvement in these diseases and its potential to disrupt the underlying cellular processes that are causing these conditions.

One of the key challenges in studying SPART is its complex structure. SPART is a transmembrane protein, which means that it spans the cell membrane and is associated with various intracellular structures. This makes it difficult to study because it is not clear where the protein interacts with its surroundings.

However, researchers have been able to study some of the key functions of SPART by using a technique called yeast two-hybrid. This technique allows researchers to study the interactions between SPART and various small molecules, such as drugs, toxins, or other proteins. By using yeast two-hybrid, researchers have been able to identify several key interactions between SPART and its ligands, which have important implications for understanding the biology of SPART.

SPART has also been shown to play a key role in several cellular processes that are important for cell survival and function. For example, SPART is involved in the regulation of cell division, which is critical for the growth and development of tissues. It is also involved in the development and maintenance of tissues, which is important for the development of organs and organs systems.

SPART is also involved in the regulation of the blood supply, which is critical for the delivery of oxygen and nutrients to tissues and the removal of waste products. This is important for maintaining the health and function of tissues and organs.

In addition to its role in cellular processes, SPART has also been shown to play a key role in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. It is often used as a potential drug target or biomarker because of its involvement in these diseases and its potential to disrupt the underlying cellular processes that are causing these conditions.

For example, SPART has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Studies have shown that SPART is involved in the regulation of the aggregation of beta-amyloid, which is a hallmark of these diseases. This suggests that SPART may be a potential target for therapies that target the production or aggregation of beta-amyloid.

SPART has also been shown to be involved in the development of autoimmune disorders, such as rheumatoid arthritis and lupus. Studies have shown that SPART is involved in the regulation of the immune response, which is critical for the development of these disorders. This suggests that SPART may be a potential target for therapies that target the immune response.

In conclusion, SPART is a protein that is involved in several cellular processes that are important for cell survival and function. It is also involved in the regulation of cell division, tissue development and maintenance, and blood supply. SPART has also been shown to play a key role in the development of several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, SPART is often used as a potential drug target or biomarker. Further research is needed to fully understand the role of SPART in these diseases and to develop effective therapies that target SPART.

Protein Name: Spartin

Functions: May be implicated in endosomal trafficking, or microtubule dynamics, or both. Participates in cytokinesis (PubMed:20719964)

The "SPART Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPART comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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