Target Name: BBC3
NCBI ID: G27113
Review Report on BBC3 Target / Biomarker Content of Review Report on BBC3 Target / Biomarker
BBC3
Other Name(s): BBC3_HUMAN | Bcl-2-binding component 3, isoforms 1/2 | JFY1 | BBC3 variant 4 | p53 up-regulated modulator of apoptosis | JFY-1 | Bcl-2-binding component 3, isoforms 1/2 (isoform 4) | BBC3 variant 1 | PUMA/JFY1 protein | Bcl-2-binding component 3 (isoform 1) | p53-upregulated modulator of apoptosis | BCL2 binding component 3, transcript variant 1 | PUMA | BCL2 binding component 3, transcript variant 4 | BCL2 binding component 3

BBC3: Potential Drug Target and Biomarker for Alzheimer's

BBC3 is a protein that is expressed in the brain and is known for its role in the development and progression of various neurological disorders, including Alzheimer's disease. The BBC3 protein is a potential drug target for the treatment of these disorders.

Research has shown that BBC3 is involved in the formation of beta-amyloid plaques, which are a hallmark of Alzheimer's disease. These plaques are thought to play a role in the destruction of nerve cells in the brain, leading to the symptoms of Alzheimer's disease. By targeting BBC3, researchers hope to reduce the formation of beta-amyloid plaques and slow the progression of the disease.

Another potential mechanism by which BBC3 may contribute to the development of Alzheimer's disease is its role in the regulation of inflammation in the brain. Inflammation is thought to play a role in the development of many neurological disorders, including Alzheimer's disease. Researchers have shown that BBC3 is involved in the regulation of inflammation in the brain, and that its levels are elevated in individuals with Alzheimer's disease.

In addition to its potential role in the development and progression of Alzheimer's disease, BBC3 is also a potential biomarker for the disease. Studies have shown that BBC3 levels are elevated in individuals with Alzheimer's disease, and that these levels can be used as a diagnostic marker for the disease. This makes BBC3 an attractive target for drug developers, as it may be possible to use it as a diagnostic tool and then target it with drugs.

Overall, BBC3 is a protein that is thought to be involved in the development and progression of Alzheimer's disease. Its potential as a drug target and as a biomarker makes it an attractive target for research into the treatment of this debilitating and progressive disease. Further research is needed to fully understand the role of BBC3 in the development and progression of Alzheimer's disease, and to determine its potential as a drug and biomarker.

Protein Name: BCL2 Binding Component 3

Functions: Does not affect cell growth

The "BBC3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about BBC3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

BBIP1 | BBLN | BBOF1 | BBOX1 | BBOX1-AS1 | BBS1 | BBS10 | BBS12 | BBS2 | BBS4 | BBS5 | BBS7 | BBS9 | BBSome complex | BBX | BCAM | BCAN | BCAN-AS1 | BCAP29 | BCAP31 | BCAR1 | BCAR3 | BCAR3-AS1 | BCAR4 | BCAS1 | BCAS2 | BCAS2P2 | BCAS3 | BCAS4 | BCAT1 | BCAT2 | BCCIP | BCDIN3D | BCDIN3D-AS1 | BCHE | BCKDHA | BCKDHB | BCKDK | BCL10 | BCL10-AS1 | BCL11A | BCL11B | BCL2 | BCL2A1 | BCL2L1 | BCL2L10 | BCL2L11 | BCL2L12 | BCL2L13 | BCL2L14 | BCL2L15 | BCL2L2 | BCL2L2-PABPN1 | BCL3 | BCL6 | BCL6B | BCL7A | BCL7B | BCL7C | BCL9 | BCL9L | BCLAF1 | BCLAF3 | BCO1 | BCO2 | BCOR | BCORL1 | BCORP1 | BCR | BCR(BACURD1) E3 ubiquitin ligase complex | BCR(BACURD3) E3 ubiquitin ligase complex | BCR(KLHL12) E3 ubiquitin ligase complex | BCR(KLHL20) E3 ubiquitin ligase complex | BCR(KLHL22) E3 ubiquitin ligase complex | BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex | BCRP2 | BCRP3 | BCRP4 | BCRP5 | BCRP6 | BCRP7 | BCS1L | BCYRN1 | BDH1 | BDH2 | BDKRB1 | BDKRB2 | BDNF | BDNF-AS | BDP1 | BEAN1 | BEAN1-AS1 | BECN1 | BECN2 | BEGAIN | BEND2 | BEND3 | BEND3P3 | BEND4 | BEND5