Target Name: SBK1
NCBI ID: G388228
Review Report on SBK1 Target / Biomarker Content of Review Report on SBK1 Target / Biomarker
SBK1
Other Name(s): SH3-binding kinase 1 | Sbk | SBK1_HUMAN | Serine/threonine-protein kinase SBK1 | SH3-binding domain kinase 1 | SBK | SH3 domain binding kinase 1

SBK1: A Key Enzyme in Cell Signaling and Disease

SH3-Binding Kinase 1 (SBK1) is a protein that is expressed in various cell types, including neurons, muscle cells, and liver cells. It is a key enzyme in the SH3 signaling pathway, which is a protein signaling pathway that regulates various cellular processes, including cell growth, differentiation, and survival.

SBK1 is a 21-kDa protein that consists of 218 amino acid residues. It has a unique structure, with a catalytic core that is composed of a nucleotide-binding domain (NBD) and a carboxy-terminal domain (CTD). The NBD is a protein-protein interaction (PPI) domain that consists of a nucleotide-binding domain and a carboxy-terminal domain. The CTD is a protein-protein interaction (PPI) domain that consists of a leucine-rich repeat (LRR) domain and a carboxy-terminal domain.

SBK1 is involved in various cellular processes, including cell signaling, DNA replication, and protein synthesis. It is a key enzyme in the SH3 signaling pathway, which is a protein signaling pathway that regulates various cellular processes, including cell growth, differentiation, and survival.

SBK1 has been shown to play a role in various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. It is a potential drug target and may be a biomarker for various diseases.

SBK1 has been shown to promote cell growth and survival in various cell types. For example, studies have shown that SBK1 can promote the growth of cancer cells in a variety of models, including in vitro and in vivo models.

SBK1 has also been shown to play a role in the regulation of DNA replication. In fact, studies have shown that SBK1 can interact with the protein DNAA1 and promote the loading of DNA into the nucleus. This interaction between SBK1 and DNAA1 may have implications for the regulation of DNA replication in cancer cells.

SBK1 has also been shown to play a role in the regulation of protein synthesis. In fact, studies have shown that SBK1 can interact with the protein SSB-1 and promote the loading of protein onto the endoplasmic reticulum. This interaction between SBK1 and SSB-1 may have implications for the regulation of protein synthesis in cancer cells.

In conclusion, SBK1 is a protein that is involved in various cellular processes, including cell signaling, DNA replication, and protein synthesis. It is a key enzyme in the SH3 signaling pathway and has been shown to promote cell growth and survival in various cell types. As a result, SBK1 may be a potential drug target and biomarker for various diseases. Further research is needed to fully understand the role of SBK1 in disease.

Protein Name: SH3 Domain Binding Kinase 1

Functions: May be involved in signal-transduction pathways related to the control of brain development

The "SBK1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SBK1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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