Target Name: SCARB1
NCBI ID: G949
Review Report on SCARB1 Target / Biomarker Content of Review Report on SCARB1 Target / Biomarker
SCARB1
Other Name(s): CD36L1 | CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1 | CLA-1 | SR-BI | SCARB1 variant 2 | SCARB1 variant 3 | Scavenger receptor class B member 1 (isoform 1) | Scavenger receptor class B member 1 | CLA1 | Scavenger receptor class B member 1, transcript variant 1 | CD36 and LIMPII analogous 1 | Scavenger receptor class B member 1, transcript variant 3 | Collagen type I receptor, thrombospondin receptor-like 1 | Scavenger receptor class B member 1 (isoform 2) | Scavenger receptor class B member 1 isoform 3 | CD36 | scavenger receptor class B type III | HDLQTL6 | SCARB1 variant 1 | Scavenger receptor class B type III | SRB1 | Scavenger receptor class B member 1, transcript variant 2 | SCRB1_HUMAN | CD36 antigen-like 1 | scavenger receptor class B member 1

CD36L1: A Protein Involved in Cell-cell Adhesion, Cell Division and Blood Vessel Formation

SCARB1 (CD36L1) is a protein that is expressed in various tissues of the body, including the nervous system, endothelial cells, and immune cells. It is a member of the SCAR family of cytoskeletal proteins, which are involved in cell-cell adhesion and cytoskeletal organization.

CD36L1 is a 21-kDa protein that is expressed in the brain, spinal cord, and peripheral tissues. It is involved in the development and maintenance of neural tube, which is the initial stage of neural development. CD36L1 is also involved in the regulation of cell adhesion and in the formation of blood vessels.

One of the key functions of CD36L1 is its role in cell-cell adhesion. CD36L1 is involved in the formation of tight junctions, which are a type of cell-cell adhesion that helps to maintain the integrity of tissues. tight junctions are formed by the interaction of CD36L1 with the cytoskeleton and other proteins that are involved in cell-cell adhesion.

CD36L1 is also involved in the regulation of cell division. It is a transcription factor that is involved in the regulation of gene expression and cell proliferation. CD36L1 is also involved in the regulation of cell differentiation, as it has been shown to play a role in the regulation of neural stem cell proliferation and differentiation.

In addition to its role in cell-cell adhesion and cell division, CD36L1 is also involved in the formation of blood vessels. It is a potent vasoactive protein that is involved in the regulation of blood vessel diameter and blood pressure. the regulation of angiogenesis, as it has been shown to play a role in the formation of new blood vessels in response to the presence of vasoactive drugs.

CD36L1 is also involved in the regulation of pain perception and neuroinflammation. It is a potent modulator of pain perception and has been shown to play a role in the regulation of neuroinflammation. CD36L1 has also been shown to be involved in the regulation of inflammation, as it has been shown to play a role in the regulation of the expression of pro-inflammatory genes.

In conclusion, CD36L1 is a protein that is involved in a wide range of physiological processes in the body. Its role in cell-cell adhesion, cell division, and blood vessel formation, as well as its involvement in the regulation of pain perception and neuroinflammation , make it an attractive drug target and a potential biomarker for a variety of diseases. Further research is needed to fully understand the role of CD36L1 in these processes and to develop effective therapies based on its properties.

Protein Name: Scavenger Receptor Class B Member 1

Functions: Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed:12016218, PubMed:12519372, PubMed:21226579). Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed:26965621). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (PubMed:12016218)

The "SCARB1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SCARB1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SCARB2 | SCARF1 | SCARF2 | SCARNA1 | SCARNA10 | SCARNA11 | SCARNA12 | SCARNA13 | SCARNA14 | SCARNA15 | SCARNA16 | SCARNA17 | SCARNA18 | SCARNA2 | SCARNA20 | SCARNA21 | SCARNA22 | SCARNA23 | SCARNA27 | SCARNA28 | SCARNA3 | SCARNA4 | SCARNA5 | SCARNA6 | SCARNA7 | SCARNA8 | SCARNA9 | SCARNA9L | SCART1 | SCAT1 | SCCPDH | SCD | SCD5 | SCDP1 | SCEL | SCF (SKP1-CUL1-F-box protein) Ubiquitin Ligase Complex | SCF Ubiquitin Ligase Complex | SCFD1 | SCFD2 | SCG2 | SCG3 | SCG5 | SCGB1A1 | SCGB1B2P | SCGB1C1 | SCGB1D1 | SCGB1D2 | SCGB1D4 | SCGB2A1 | SCGB2A2 | SCGB2B2 | SCGB3A1 | SCGB3A2 | SCGN | SCHIP1 | SCHLAP1 | SCIMP | SCIN | SCIRT | SCLT1 | SCLY | SCMH1 | SCML1 | SCML2 | SCML4 | SCN10A | SCN11A | SCN1A | SCN1A-AS1 | SCN1B | SCN2A | SCN2B | SCN3A | SCN3B | SCN4A | SCN4B | SCN5A | SCN7A | SCN8A | SCN9A | SCNM1 | SCNN1A | SCNN1B | SCNN1D | SCNN1G | SCO1 | SCO2 | SCOC | SCOC-AS1 | SCP2 | SCP2D1 | SCP2D1-AS1 | SCPEP1 | SCRG1 | SCRIB | SCRN1 | SCRN2 | SCRN3 | SCRT1 | SCRT2