Target Name: SCG3
NCBI ID: G29106
Review Report on SCG3 Target / Biomarker Content of Review Report on SCG3 Target / Biomarker
SCG3
Other Name(s): SGIII | Secretogranin-3 (isoform 1) | Secretogranin III, transcript variant 1 | Secretogranin 3 | secretogranin III | SgIII | SCG3_HUMAN | Secretogranin-3 | FLJ90833 | SCG3 variant 1 | Secretogranin III

SGI3: A Promising Drug Target and Biomarker for Disabilities

SCG3 (SGIII) is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidneys. It is a member of the SGI family, which includes several similar proteins that play important roles in cellular signaling. One of the key functions of SGI proteins is to transmit signals from the cell surface to intracellular signaling pathways, which can regulate a wide range of cellular processes, including cell survival, growth, and metabolism.

Recent studies have identified SGI3 as a potential drug target for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is because SGI3 is involved in a number of important cellular processes that are disrupted in these conditions, and because it is a relatively stable protein that is expressed in a wide range of tissues.

One of the key reasons why SGI3 is thought to be a promising drug target is that it is involved in a number of important signaling pathways that are involved in cancer, neurodegenerative diseases, and autoimmune disorders. For example, SGI3 has been shown to be involved in the regulation of cell proliferation, apoptosis (programmed cell death), and inflammation. It has also been shown to play important roles in the development and progression of several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease.

In addition to its involvement in these important cellular processes, SGI3 is also a protein that is thought to be involved in the regulation of the immune system. This is because it is expressed in a wide range of tissues and is highly conserved across different species, which suggests that it is involved in a wide range of important biological processes that are important for the immune system.

Given the importance of SGI3 in a wide range of cellular processes, it is a promising candidate for drug development. Researchers are currently working to identify small molecules that can specifically interact with SGI3 and modulate its activity. These small molecules are thought to be able to inhibit the activity of SGI3, which could potentially lead to the treatment of a wide range of diseases.

In addition to its potential as a drug target, SGI3 is also a potential biomarker for several diseases. This is because it is a protein that is expressed in a wide range of tissues, which suggests that it is a good candidate for use as a biomarker for a wide range of diseases. For example, SGI3 has been shown to be expressed in the brains of individuals with Alzheimer's disease, which suggests that it may be a useful biomarker for this disease. Similarly, SGI3 has been shown to be expressed in the brains of individuals with Parkinson's disease, which suggests that it may be a useful biomarker for this disease.

Overall, SGI3 is a protein that is thought to be involved in a wide range of important cellular processes, including cell proliferation, apoptosis, and inflammation. It is a potential drug target for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders, and is also a potential biomarker for these conditions. Further research is needed to fully understand the role of SGI3 in these processes and to identify small molecules that can specifically interact with it.

Protein Name: Secretogranin III

Functions: Member of the granin protein family that regulates the biogenesis of secretory granules (PubMed:19357184). Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA (By similarity). May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway (PubMed:29154827)

The "SCG3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SCG3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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SCG5 | SCGB1A1 | SCGB1B2P | SCGB1C1 | SCGB1D1 | SCGB1D2 | SCGB1D4 | SCGB2A1 | SCGB2A2 | SCGB2B2 | SCGB3A1 | SCGB3A2 | SCGN | SCHIP1 | SCHLAP1 | SCIMP | SCIN | SCIRT | SCLT1 | SCLY | SCMH1 | SCML1 | SCML2 | SCML4 | SCN10A | SCN11A | SCN1A | SCN1A-AS1 | SCN1B | SCN2A | SCN2B | SCN3A | SCN3B | SCN4A | SCN4B | SCN5A | SCN7A | SCN8A | SCN9A | SCNM1 | SCNN1A | SCNN1B | SCNN1D | SCNN1G | SCO1 | SCO2 | SCOC | SCOC-AS1 | SCP2 | SCP2D1 | SCP2D1-AS1 | SCPEP1 | SCRG1 | SCRIB | SCRN1 | SCRN2 | SCRN3 | SCRT1 | SCRT2 | SCT | SCTR | SCUBE1 | SCUBE2 | SCUBE3 | SCXA | SCYL1 | SCYL2 | SDAD1 | SDAD1-AS1 | SDAD1P1 | SDC1 | SDC2 | SDC3 | SDC4 | SDCBP | SDCBP2 | SDCBP2-AS1 | SDCBPP2 | SDCCAG8 | SDE2 | SDF2 | SDF2L1 | SDF4 | SDHA | SDHAF1 | SDHAF2 | SDHAF3 | SDHAF4 | SDHAP1 | SDHAP2 | SDHAP3 | SDHAP4 | SDHB | SDHC | SDHD | SDHDP1 | SDHDP2 | SDK1 | SDK1-AS1 | SDK2