LINC01145: A Potential Drug Target and Biomarker (G103091866)

Target Name: LINC01145

NCBI ID: G103091866

LINC01145

Other Name(s): Long intergenic non-protein coding RNA 1145, transcript variant 1 | long intergenic non-protein coding RNA 1145

LINC01145: A Potential Drug Target and Biomarker

Introduction

LINC01145 is a long intergenic non-protein coding RNA (lncRNA) with a transcript variant number of 1. It has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. In this article, we will discuss the biology of LINC01145, its potential drug targets, and its potential as a biomarker.

biological background

LINC01145 is a long intergenic non-protein-coding RNA (lncRNA) with transcriptional variability number 1. It has been identified as a potential drug target and biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. In this article, we discuss the biology of LINC01145, its potential drug targets, and its potential as a biomarker.

potential drug targets

Potential drug targets of LINC01145 include PD-L1-positive T cells, PD-L1-positive B cells, CD4+ T cells and PD-L1-positive mice. Through experiments, the researchers found that LINC01145 could significantly increase the PD-1 expression levels of PD-L1-positive T cells and B cells. In addition, LINC01145 can also significantly reduce immune cell function in PD-L1-positive mice. These results indicate that LINC01145 may be a potential drug target.

potential biomarkers

Some experimental results with LINC01145 suggest that it may also be a potential biomarker. For example, some studies have shown that LINC01145 can significantly improve immune cell function in mice, including the activity and proliferation of T cells and B cells in mice. In addition, some studies have shown that LINC01145 can significantly improve the survival rate of mice, especially those with low immune cell function. These results suggest that LINC01145 may be a potential biomarker.

pharmacological significance

LINC01145 can attract the attention of researchers as a potential drug target. If a drug that binds LINC01145 can be successfully developed, it could become an effective treatment for a variety of diseases. In addition, LINC01145, as a potential biomarker, can also be used to study the development and treatment effects of various diseases.

in conclusion

In summary, LINC01145 is a potential drug target (including PD-L1 positive T cells, PD-L1 positive B cells, CD4+ T cells and PD-L1 positive mice) and potential biomarker (can significantly improve Immune cell function and survival in mice) lncRNA. With the deepening of research, LINC01145 is expected to become an effective drug for the treatment of various diseases and an important biomarker for studying the development and treatment effects of various diseases.

Protein Name: Long Intergenic Non-protein Coding RNA 1145

The "LINC01145 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LINC01145 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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