LINC01128: A Long Intergenic Non-Protein Coding RNA and Its Potential as a Drug Target

Target Name: LINC01128

NCBI ID: G643837

LINC01128

Other Name(s): Long intergenic non-protein coding RNA 1128, transcript variant 1 | long intergenic non-protein coding RNA 1128

LINC01128: A Long Intergenic Non-Protein Coding RNA and Its Potential as a Drug Target

Introduction

LINC01128 is a long non-protein-coding RNA (lncRNA) molecule, located on chromosome 6p21.2, has been identified as a potential drug target and biomarker. It is characterized by its unique structure, which consists of a long intergenic RNA molecule with a conserved open reading frame (ORF) that is predominantly transcribed in the brain.

Molecular Characterization

LINC01128 is 1,947 nucleotides long and has a calculated exon-intron ratio of 12.46. It is predominantly transcribed in the brain and has been shown to be expressed in various tissues and cell types, including brain, heart, and muscle. The ORF of LINC01128 is 194 nucleotides long and includes 11 different exons.

Expression and Function

LINC01128 has been shown to play a role in various brain functions, including cell survival, neurotransmitter synthesis, and stress response. It has been shown to be involved in the regulation of cell adhesion, migration, and the formation of neurotransmitter systems.

In addition, LINC01128 has been shown to be involved in the regulation of inflammation and has been linked to the production of pro-inflammatory cytokines. This may have important implications for the development of neuroinflammatory diseases, such as Alzheimer's disease and Parkinson's disease.

Drug Target Potential

The unique structure and function of LINC01128 make it an attractive drug target. Because it has a long non-coding RNA molecule and it plays an important role in multiple biological processes, the response to the drug may be more responsive than other molecules. To be obvious.

Furthermore, since LINC01128 exists in multiple species, it could be used as a potential drug to treat neurodegenerative diseases in various animal models, such as Alzheimer's disease and Parkinson's disease.

Conclusion

LINC01128 is a long non-protein-coding RNA molecule that has been identified as a potential drug target and biomarker. Its unique structure and function make it an attractive target for drug development. Further research is needed to fully understand the role of LINC01128 in various biological processes and its potential as a drug.

Protein Name: Long Intergenic Non-protein Coding RNA 1128

The "LINC01128 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LINC01128 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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