MIR107: A Non-Coding RNA Molecule as A Potential Drug Target (G406901)
MIR107: A Non-Coding RNA Molecule as A Potential Drug Target
MIR107 (MIRN107) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. MIR107 is a small non-coding RNA molecule that plays a role in the regulation of gene expression. It is expressed in various tissues and cells throughout the body and has been shown to be involved in the regulation of various cellular processes, including cell growth, differentiation, and inflammation.
One of the unique features of MIR107 is its ability to interact with other non-coding RNA molecules, including microRNAs (miRNAs). MIR107 has been shown to function as a negative regulator of miRNA 21 (miR-21), which is a well- known regulator of cell growth and differentiation. MIR107 has been shown to inhibit the activity of miR-21, which leads to the production of larger, less stable miRNAs.
In addition to its role in regulating miRNA levels, MIR107 has also been shown to play a role in the regulation of gene expression more broadly. It has been shown to interact with various protein molecules, including transcription factors. Through these interactions, MIR107 can regulate gene expression, thereby affecting a variety of biological processes.
Target of MIR107
The target of MIR107 is miR-21. miR-21 is a non-coding RNA molecule with a length of approximately 200 nucleotides, which plays an important biological role in cells, especially during cell proliferation and differentiation. Studies have shown that MIR107 inhibits the activity of miR-21 by binding to it, thereby affecting the regulation of gene expression by miR-21.
Detection of MIR107
To detect the expression levels and functions of MIR107 in cells, the researchers used a technology called "gene expression sequencing." They first extracted RNA from intestinal epithelial cells and used a sequencer to sequence the RNA. They found that MIR107 was expressed at a high level in cells, and its expression level increased as the cell cycle progressed. In addition, they also found that the combination of MIR107 and miR-21 plays a key role in cell proliferation and differentiation.
Clinical applications of MIR107
As a potential drug target, MIR107 has broad application prospects in the field of drug research and development. Currently, researchers are exploring MIR107 as a drug target to treat various diseases. In particular, they are investigating whether MIR107 could serve as a drug target to treat cancer. Research shows that MIR107 can significantly inhibit the growth and spread of cancer cells, thus providing a new idea for cancer treatment.
Biological functions of MIR107
MIR107 has multiple biological functions in cell biology. First, MIR107 can regulate the cell cycle, thereby affecting cell proliferation and differentiation. Secondly, MIR107 can regulate cell apoptosis to maintain cellular homeostasis. In addition, MIR107 can also regulate cell migration and cell differentiation, thereby playing an important role in tissue and organ formation.
Pathological functions of MIR107
MIR107 also has pathological functions in certain diseases. For example, studies have shown that MIR107 can regulate the growth and spread of tumor cells, thereby playing an important role in tumor growth and development. In addition, MIR107 can also regulate the differentiation and function of immune cells, thereby participating in immune surveillance and immunotherapy.
Pharmacological significance of MIR107
As a non-coding RNA molecule, MIR107 has broad application prospects in the field of pharmacology. Currently, researchers are exploring MIR107 as a drug target to treat various diseases. In particular, they are investigating whether MIR107 could serve as a drug target to treat cancer. Research shows that MIR107 can significantly inhibit the growth and spread of cancer cells, thus providing a new idea for cancer treatment.
Protein Name: MicroRNA 107
The "MIR107 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR107 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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