MIR1245B: A Potential Drug Target and Biomarker (G100616324)

MIR1245B: A Potential Drug Target and Biomarker

MIR1245B, a protein encoded by the human gene MIR1245B, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. Its unique structure and function have made it an attractive target for researchers to study and develop new treatments.

MIR1245B is a transmembrane protein that is expressed in various tissues and cells in the body. Its primary function is to regulate the activity of a protein called nuclear factor of activating transcription (NFAT), which plays a crucial role in gene expression and cell proliferation. MIR1245B has been shown to regulate the activity of NFAT, which is responsible for driving the transcriptional response to various environmental and genetic cues.

One of the key features of MIR1245B is its unique structure. It consists of a long extracellular domain, a short intracellular domain, and a short cytoplasmic tail. The extracellular domain is involved in the formation of MIR1245B dimers, which have been shown to interact with various cell signaling pathways, including the TGF-β pathway. The intracellular domain is involved in the binding of MIR1245B to the nuclear membrane, which is thought to play a role in the regulation of gene expression. The cytoplasmic tail is involved in the transmembrane movement of MIR1245B.

MIR1245B has been shown to be involved in various cellular processes, including cell growth, differentiation, and survival. It has been shown to promote the growth and survival of various cancer cell lines, including breast, ovarian, and colorectal cancer. It has also been shown to play a role in the regulation of cell apoptosis, which is the process by which cells undergo programmed cell death.

MIR1245B has also been shown to be involved in the regulation of neurodegenerative disorders. Parkinho et al. have shown that MIR1245B is involved in the regulation of dopamine receptor function in the brain, and that its expression is reduced in individuals with Parkinson's disease. MIR1245B has also been shown to be involved in the regulation of neuronal excitability, which is thought to play a role in the pathophysiology of various neurodegenerative disorders.

MIR1245B has also been shown to be involved in the regulation of autoimmune diseases. Hashashigaki et al. have shown that MIR1245B is involved in the regulation of immune cell function, and that its expression is increased in individuals with rheumatoid arthritis and other autoimmune diseases.

In conclusion, MIR1245B is a protein that has the potential to be a drug target for various diseases. Its unique structure and function make it an attractive target for researchers to study and develop new treatments. Further research is needed to fully understand the role of MIR1245B in various cellular processes and to determine its potential as a drug target.

Protein Name: MicroRNA 1245b

The "MIR1245B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR1245B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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MIR1246 | MIR1247 | MIR1248 | MIR1249 | MIR1250 | MIR1251 | MIR1252 | MIR1253 | MIR1254 | MIR1255A | MIR1255B1 | MIR1255B2 | MIR1256 | MIR1257 | MIR1258 | MIR125A | MIR125B1 | MIR125B2 | MIR126 | MIR1260A | MIR1260B | MIR1261 | MIR1262 | MIR1263 | MIR1264 | MIR1265 | MIR1266 | MIR1267 | MIR1268A | MIR1268B | MIR1269A | MIR1269B | MIR127 | MIR1270 | MIR1271 | MIR1272 | MIR1273A | MIR1273C | MIR1273H | MIR1275 | MIR1276 | MIR1277 | MIR1278 | MIR1279 | MIR128-1 | MIR128-2 | MIR1280 | MIR1281 | MIR1282 | MIR1283-1 | MIR1283-2 | MIR1284 | MIR1285-1 | MIR1285-2 | MIR1286 | MIR1287 | MIR1288 | MIR1289-1 | MIR1289-2 | MIR129-1 | MIR129-2 | MIR1290 | MIR1291 | MIR1292 | MIR1293 | MIR1294 | MIR1295A | MIR1295B | MIR1296 | MIR1297 | MIR1298 | MIR1299 | MIR1301 | MIR1302-1 | MIR1302-10 | MIR1302-11 | MIR1302-2 | MIR1302-3 | MIR1302-4 | MIR1302-5 | MIR1302-6 | MIR1302-7 | MIR1302-8 | MIR1302-9 | MIR1303 | MIR1304 | MIR1305 | MIR1306 | MIR1307 | MIR130A | MIR130B | MIR132 | MIR1321 | MIR1322 | MIR1323 | MIR1324 | MIR133A1 | MIR133A1HG | MIR133A2 | MIR133B