Target Name: MIR197
NCBI ID: G406974
Review Report on MIR197 Target / Biomarker Content of Review Report on MIR197 Target / Biomarker
MIR197
Other Name(s): microRNA 197 | MIRN197 | MiR-197 | hsa-miR-197-5p | MicroRNA 197 | miR-197 | MiRNA197 | hsa-mir-197 | hsa-miR-197-3p | miRNA197

MIR197: A Non-Coding RNA Molecule and Its Potential Applications

MicroRNA (miRNA) 197 (MIR197) is a non-coding RNA molecule that plays a critical role in various biological processes in the cell. MIR197 is composed of 202 amino acid residues and has a typical length of approximately 20-22 nts. It is expressed in various tissues and cells throughout the body, including the brain, heart, liver, and muscle.

MIR197 is a negative regulator of gene expression, which means that it works to reduce the amount of a particular gene's products in the cell. It does this by binding to a specific target gene's mRNA and causing it occurs to be degraded. This degradation through a process called translation-dependent degradation (TAD), which involves the cleavage of the bonds between the mRNA and the protein chaperone.

MIR197 has been shown to play a role in various cellular processes, including cell growth, apoptosis, and inflammation. It has also been implicated in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

One of the most promising applications of MIR197 is as a drug target. The discovery of MIR197 as a potential drug target has led to a great deal of research and development in the field of drug discovery, with the goal of identifying and designing small molecules that can inhibit the activity of MIR197 and its downstream targets.

Several studies have shown that MIR197 can be effectively inhibited by small molecules, such as inhibitors of the translation elongation complex (TEC), which is a critical component of the machinery that translates mRNA into protein. These inhibitors can cause MIR197 to stability, which can lead to a reduction in its levels in the cell.

Another approach to inhibiting MIR197 is through the use of small molecules that specifically interact with its C-terminus. These small molecules can cause MIR197 to enter a state of hyperactivity, which can lead to an increase in its levels in the cell.

In addition to its potential as a drug target, MIR197 has also been shown to be a valuable biomarker for various diseases. The levels of MIR197 have been shown to be reduced in the brains of individuals with certain neurological disorders, such as Alzheimer's disease and Parkinson's disease. This suggests that MIR197 may be a useful diagnostic or therapeutic target for these disorders.

Overall, MIR197 is a highly promising molecule for drug discovery and biomarker development. Further research is needed to fully understand its role in various biological processes and to develop effective small molecules that can inhibit its activity.

Protein Name: MicroRNA 197

The "MIR197 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR197 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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