BFSP2: Potential Drug Target and Biomarker for Brain Function

Target Name: BFSP2

NCBI ID: G8419

BFSP2

BFSP2: Potential Drug Target and Biomarker for Brain Function

BFSP2 (Brain-FGF signaling protein 2) is a protein that is expressed in various tissues of the body, including the brain. It is a member of the family of FGF (fibroblast growth factor) proteins, which are known for their role in cell growth, maintenance, and regeneration. BFSP2 has been shown to play a role in several physiological processes in the brain, including the development and maintenance of neuronal connectivity.

One of the unique features of BFSP2 is its ability to interact with other proteins that are involved in the neural circuitry of the brain. This interaction is mediated by its FGF-like domain, which is known for its ability to interact with FGF-like proteins. BFSP2 has been shown to play a role in several neural circuitry processes, including the development of synaptic connections between neurons and the regulation of neurotransmitter release.

In addition to its role in neural circuitry, BFSP2 has also been shown to play a role in several other physiological processes in the brain. For example, it has been shown to be involved in the regulation of cell death, stem cell maintenance, and plasticity. BFSP2 has also been shown to play a role in the regulation of inflammation, which is important for the immune response to infection and injury.

Due to its involvement in several important physiological processes in the brain, BFSP2 has been identified as a potential drug target. Researchers have shown that BFSP2 can be targeted with small molecules, including inhibitors of its FGF-like domain. These inhibitors have been shown to have a variety of different effects on brain function, including the regulation of neuronal connectivity and the modulation of neurotransmitter release.

In addition to its potential as a drug target, BFSP2 also has the potential as a biomarker for several neurological disorders. For example, BFSP2 has been shown to be involved in the development of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. This suggests that BFSP2 may be a useful biomarker for these disorders, as well as other neurological conditions such as depression and anxiety.

Overall, BFSP2 is a protein that has significant involvement in several important physiological processes in the brain. Its ability to interact with other proteins involved in neural circuitry makes it a promising target for small molecules, and its potential as a biomarker for neurological disorders makes it an important molecule to study further. Further research is needed to fully understand the role of BFSP2 in neural circuitry and its potential as a drug and biomarker.

Protein Name: Beaded Filament Structural Protein 2

Functions: Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA (PubMed:28935373). Plays a role in maintenance of retinal lens optical clarity (By similarity)

The "BFSP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about BFSP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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