Target Name: BFAR
NCBI ID: G51283
Review Report on BFAR Target / Biomarker Content of Review Report on BFAR Target / Biomarker
BFAR
Other Name(s): RNF47 | RING finger protein 47 | Bifunctional apoptosis regulator (isoform 1) | BFAR variant 1 | Bifunctional apoptosis regulator, transcript variant 1 | Bifunctional apoptosis regulator | BFAR_HUMAN | bifunctional apoptosis inhibitor | Bifunctional apoptosis inhibitor | bifunctional apoptosis regulator | BAR

BFAR: A Potential Drug Target for Neurodegenerative Diseases

BFAR (Brain-FGF-Activated Receptor) is a protein that is expressed in the nervous system and has been identified as a potential drug target in the field of neurodegenerative diseases. The full name of the receptor is BFAR-related neurotrophic factor (BFAR), and it is a member of the TGF-β receptor superfamily. This protein is involved in the development and progression of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases.

The BFAR protein is composed of 115 amino acid residues and has a calculated molecular weight of 13.9 kDa. It is expressed in the central nervous system (CNS) and is involved in the development and progression of neurodegenerative diseases. The BFAR protein is a potent negative regulator of the TGF-β pathway, which is a well-established pathway involved in the development and progression of neurodegenerative diseases.

The TGF-β pathway is a complex intracellular signaling pathway that is involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases. The TGF-β pathway is a transcription factor that regulates the expression of genes involved in the development and progression of neurodegenerative diseases. The BFAR protein is involved in the regulation of the TGF-β pathway by inhibiting the activity of the TGF-β receptor.

The BFAR protein is involved in the development and progression of neurodegenerative diseases by regulating the TGF-β pathway. The TGF-β pathway is involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases. The BFAR protein is a potent negative regulator of the TGF-β pathway, which means that it inhibits the activity of the TGF-β receptor and protects against the development and progression of neurodegenerative diseases.

The BFAR protein is also involved in the regulation of cell survival and proliferation. It is a negative regulator of the TGF-β pathway, which means that it inhibits the activity of the TGF-β receptor and protects against the development and progression of neurodegenerative diseases. The BFAR protein helps to maintain the stability of the nervous system by regulating the number of neurons that are produced and the duration of their life.

The BFAR protein is also involved in the regulation of neurotransmitter release. It is a negative regulator of the TGF-β pathway, which means that it inhibits the activity of the TGF-β receptor and protects against the development and progression of neurodegenerative diseases. The BFAR protein helps to regulate the release of neurotransmitters, such as dopamine and nitric oxide, which are involved in the transmission of signals in the nervous system.

The BFAR protein is also involved in the regulation of inflammation. It is a negative regulator of the TGF-β pathway, which means that it inhibits the activity of the TGF-β receptor and protects against the development and progression of neurodegenerative diseases. The BFAR protein helps to regulate the production of pro-inflammatory cytokines, which are involved in the development of neurodegenerative diseases.

The BFAR protein is also involved in the regulation of cell migration. It is a negative regulator of the TGF-β pathway, which means that it inhibits the activity of the TGF-β receptor and protects against the development and progression of neurodegenerative diseases. The BFAR protein helps to maintain the stability of the nervous system by regulating the movement of neurons and glial cells.

In conclusion, the BFAR protein is a potential drug target for the development of neurodegenerative diseases. The BFAR protein is involved in the development and progression of neurodegenerative diseases by regulating the TGF-β pathway. The BFAR protein is a potent negative regulator of the TGF-β pathway and is involved in the regulation of cell survival and proliferation, neurotransmission, inflammation, and cell migration. These properties make the BFAR protein an attractive target

Protein Name: Bifunctional Apoptosis Regulator

Functions: Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors

The "BFAR Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about BFAR comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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