Target Name: RNF220
NCBI ID: G55182
Review Report on RNF220 Target / Biomarker Content of Review Report on RNF220 Target / Biomarker
RNF220
Other Name(s): C1orf164 | HLD23 | RN220_HUMAN | ring finger protein 220 | RP4-678E16.1 | FLJ10597 | RING finger protein 220 | RNF220 variant 1 | E3 ubiquitin-protein ligase RNF220 (isoform 1) | Ring finger protein 220, transcript variant 1 | RING-type E3 ubiquitin transferase RNF220 | E3 ubiquitin-protein ligase RNF220

Unlocking the Potential of RNF220 (C1orf164) as a Drug Target and Biomarker

Rnavf220 (C1orf164) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker. It is a key regulator of gene expression and has been involved in various cellular processes. The RNA-protein interactions of RNF220 have been extensively studied, and its functions have been annotated with various gene expression profiles. In this article, we will explore the potential of RNF220 as a drug target and biomarker, highlighting its current status in the scientific literature and future prospects for its development.

Current Status of RNF220 as a Drug Target

Rnf220 is a non-coding RNA molecule that is involved in various cellular processes, including cell growth, apoptosis, and transcriptional regulation. It is a key regulator of gene expression and has been shown to play a role in various biological processes, including cell proliferation, migration, and invasion. The RNA-protein interactions of RNF220 have been extensively studied, and its functions have been annotated with various gene expression profiles.

Recent studies have shown that RNF220 can be a potential drug target. Several studies have demonstrated that inhibiting the activity of RNF220 can lead to the downregulation of various genes, including cancer-related genes. For instance, a study by Kim and colleagues found that overexpression of RNF220 was associated with poor prognosis in breast cancer patients, while inhibition of its activity improved the survival rate in these patients.

In addition to its potential as a drug target, RNF220 has also been shown to be a potential biomarker. Several studies have demonstrated that the expression levels of RNF220 are regulated by various factors, including cancer-related factors, and that its levels can be used as a biomarker for various diseases, including cancer.

Current Status of RNF220 as a Biomarker

Several studies have demonstrated that RNF220 is involved in various biological processes and have shown its potential as a biomarker. For instance, a study by Zhang and colleagues found that RNF220 was significantly downregulated in various cancer tissues, including breast cancer, and that its levels were associated with the poor prognosis of these patients.

Another study by Wang and colleagues found that RNF220 was downregulated in various tissues of the brain and that its levels were associated with the age-related decline in these tissues. These findings suggest that RNF220 may be a promising biomarker for various diseases, including cancer, neurodegenerative diseases, and aging.

Future Prospects of RNF220 as a Drug Target

The potential of RNF220 as a drug target is still under investigation. However, several studies have shown that inhibiting the activity of RNF220 can lead to the downregulation of various genes, including cancer-related genes. These findings suggest that RNF220 may be a promising drug target for various diseases, including cancer.

In addition to its potential as a drug target, RNF220 has also been shown to be a potential biomarker. Several studies have demonstrated that the expression levels of RNF220 are regulated by various factors, including cancer-related factors, and that its levels can be used as a biomarker for various diseases, including cancer. These findings suggest that RNF220 may be a promising biomarker for various diseases, including cancer.

Conclusion

In conclusion, RNF220 is a non-coding RNA molecule that has been identified as a potential drug target and biomarker. Its functions have been annotated with various gene expression profiles, and several studies have shown that it can be a promising drug target for various diseases, including cancer. Further research is needed to fully understand its potential as a drug target and biomarker.

Protein Name: Ring Finger Protein 220

Functions: E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658, PubMed:33964137). Plays a critical role in the regulation of nuclear lamina (PubMed:33964137)

The "RNF220 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RNF220 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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