Target Name: REN
NCBI ID: G5972
Review Report on REN Target / Biomarker Content of Review Report on REN Target / Biomarker
REN
Other Name(s): Angiotensin-forming enzyme | angiotensinogenase | renin precursor, renal | Renin precursor, renal | RTD | angiotensin-forming enzyme | Renin | HNFJ2 | renin | Angiotensinogenase | RENI_HUMAN | ADTKD4

Understanding The Role of Ren in The Body

Ren is a protein that is expressed in many different tissues throughout the body. It is a key enzyme in the renin-angiotensin-aldosterone system, which is responsible for regulating blood pressure and fluid balance in the body. While the exact function of Ren is not fully understood, it is known to play a key role in the regulation of sodium and water intake, as well as the production of angiotensin II, a hormone that contributes to blood pressure and inflammation.

Recent studies have suggested that Ren may be a drug target or biomarker for a variety of conditions, including hypertension, heart failure, and chronic kidney disease. This is because of the key role that Ren plays in the regulation of these conditions, as well as its involvement in several other physiological processes that are important for overall health.

One of the key functions of Ren is its role in the regulation of sodium and water intake. This is important for maintaining the proper balance of fluids in the body, which is essential for many different functions, including maintaining blood pressure, providing a medium for the transport of nutrients, and maintaining the proper functioning of the nervous system.

In addition to its role in fluid balance, Ren is also involved in the production of angiotensin II. This hormone is known to contribute to the development and maintenance of high blood pressure, as well as inflammation throughout the body. The production of angiotensin II is Regulated by several factors, including the level of sodium in the body and the levels of certain enzymes in the renin-angiotensin-aldosterone system.

Recent studies have suggested that the levels of Ren may be an important indicator of the overall health of the body. For example, one study found that individuals with high levels of Ren may be at increased risk of developing heart failure, a condition in which the The heart is unable to pump enough blood to meet the body's needs. This suggests that monitoring Ren levels may be a useful diagnostic tool for heart failure.

Another study found that individuals with high levels of Ren may be at increased risk of developing chronic kidney disease, a condition in which the kidneys are not able to function properly. This suggests that monitoring Ren levels may be a useful diagnostic tool for chronic kidney disease.

In addition to its involvement in the regulation of sodium and water intake, Ren is also involved in the production of angiotensin II. This hormone is known to contribute to the development and maintenance of high blood pressure, as well as inflammation throughout the body. Production of angiotensin II is regulated by several factors, including the level of sodium in the body and the levels of certain enzymes in the renin-angiotensin-aldosterone system.

Recent studies have suggested that the levels of Ren may be an important indicator of the overall health of the body. For example, one study found that individuals with high levels of Ren may be at increased risk of developing heart failure, a condition in which the The heart is unable to pump enough blood to meet the body's needs. This suggests that monitoring Ren levels may be a useful diagnostic tool for heart failure.

Another study found that individuals with high levels of Ren may be at increased risk of developing chronic kidney disease, a condition in which the kidneys are not able to function properly. This suggests that monitoring Ren levels may be a useful diagnostic tool for chronic kidney disease.

While the exact function of Ren is not fully understood, it is known to play a key role in the regulation of sodium and water intake, as well as the production of angiotensin II. As such, monitoring Ren levels may be a useful tool for the diagnosis and treatment of conditions that are related to these processes. Additionally, the study of Ren's potential as a drug target or biomarker for various diseases has implications for the development of new treatments for a variety of conditions.

Protein Name: Renin

Functions: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney

The "REN Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about REN comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

RENBP | REP15 | Repeat-binding factor | REPIN1 | Replication factor C | Replication Protein A Complex (RPA) | REPS1 | REPS2 | RER1 | RERE | REREP3 | RERG | RERGL | RESF1 | RESP18 | REST | RET | Retinoid acid receptor | Retinoid RXR receptor | Retinol dehydrogenase | RETN | RETNLB | RETREG1 | RETREG2 | RETREG3 | RETSAT | REV1 | REV3L | Reverse transcriptase (Telomerase) | REX1BD | REXO1 | REXO1L1P | REXO1L2P | REXO1L6P | REXO1L8P | REXO2 | REXO4 | REXO5 | RFC1 | RFC2 | RFC3 | RFC4 | RFC5 | RFESD | RFESDP1 | RFFL | RFK | RFLNA | RFLNB | RFNG | RFPL1 | RFPL1S | RFPL2 | RFPL3 | RFPL3S | RFPL4A | RFPL4AL1 | RFPL4B | RFT1 | RFTN1 | RFTN2 | RFWD3 | RFX complex | RFX1 | RFX2 | RFX3 | RFX3-DT | RFX4 | RFX5 | RFX5-AS1 | RFX6 | RFX7 | RFX8 | RFXANK | RFXAP | RGCC | RGL1 | RGL2 | RGL3 | RGL4 | RGMA | RGMB | RGMB-AS1 | RGN | RGP1 | RGPD1 | RGPD2 | RGPD3 | RGPD4 | RGPD4-AS1 | RGPD5 | RGPD6 | RGPD8 | RGR | RGS1 | RGS10 | RGS11 | RGS12 | RGS13 | RGS14