Roc1: A GTP-Binding Protein with Potential as A Drug Target Or Biomarker

Target Name: RIT1

NCBI ID: G6016

RIT1

Roc1: A GTP-Binding Protein with Potential as A Drug Target Or Biomarker

GTP-binding proteins are a family of proteins that play a crucial role in intracellular signaling. They are involved in regulating various cellular processes, including cell growth, differentiation, and signaling pathways. One such protein is Roc1, which is a member of the GTP -binding protein family and has been identified as a potential drug target or biomarker.

Roc1 is a 21-kDa protein that is expressed in various tissues, including muscle, heart, and brain. It is highly conserved, with a calculated pI of 5.9, which makes it a good candidate for drug targeting. Roc1 functions as a GTP- binding protein by interacting with the nucleotide GDP. This interaction allows Roc1 to regulate various cellular processes, including cell signaling, DNA replication, and protein synthesis.

One of the unique features of Roc1 is its ability to interact with different nucleotides, including GTP, ATP, and CTP. This interactivity makes Roc1 a versatile protein that can be used as a drug target or biomarker. Roc1 has been shown to interact with various small molecules, including inhibitors of the protein kinase A, which is involved in cell signaling.

In addition to its potential as a drug target, Roc1 has also been identified as a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. This is because its interaction with different nucleotides makes it a useful indicator of cellular stress, which can be indicative of disease.

One of the reasons why Roc1 has potential as a drug target is its involvement in various signaling pathways. For example, studies have shown that Roc1 can interact with the protein kinase A, which is involved in cell signaling. This interaction suggests that Roc1 may be Involved in regulating cellular signaling pathways, including the regulation of cell growth, differentiation, and survival.

Furthermore, Roc1 has also been shown to interact with the protein kinaseB, which is involved in cell signaling and DNA replication. This interaction suggests that Roc1 may be involved in regulating the DNA replication process and may have implications for the development of cancer.

Another potential drug target for Roc1 is its role in regulating protein synthesis. Studies have shown that Roc1 can interact with the protein translation factor4 (PTF4), which is involved in regulating protein synthesis. This interaction suggests that Roc1 may be involved in regulating protein synthesis and may have implications for the development of neurodegenerative diseases.

In conclusion, Roc1 is a GTP-binding protein that has various roles in intracellular signaling. Its interaction with different nucleotides makes it a potential drug target or biomarker, and its involvement in various signaling pathways and protein synthesis regulations suggest that it may have implications for the development of various diseases. Further research is needed to fully understand the role of Roc1 in cellular signaling and its potential as a drug target or biomarker.

Protein Name: Ras Like Without CAAX 1

Functions: Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation

The "RIT1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RIT1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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