Target Name: MIR487A
NCBI ID: G619555
Review Report on MIR487A Target / Biomarker Content of Review Report on MIR487A Target / Biomarker
MIR487A
Other Name(s): MIRN487 | hsa-miR-487a-3p | hsa-mir-487 | mir-487a | MIRN487A | hsa-miR-487a-5p | hsa-mir-487a | MicroRNA 487a | microRNA 487a

MIR487A: A Potential Drug Target and Biomarker

Molecular Intelligence and Review

MIR487A, a gene encoding a protein known as MIR487A, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and psychiatric disorders. Its unique structure and function have made it an attractive target for drug development, and recent studies have provided valuable insights into its potential as a drug.

Structure and Function

MIR487A is a member of the star family, belonging to the conserved domain of the P120 subfamily, with highly conserved conserved residues, including conserved amino acid sequences and conserved secondary structures. It is a protein composed of 96 amino acids and its molecular weight is 11.9 kDa. MIR487A has an N-terminal 伪-helix, a central 尾-sheet and a C-terminal domain. In addition, it has a unique C-helical structure, which is composed of two complementary helices and has high secondary structure plasticity. The secondary structure of MIR487A can be interpreted as a tightly bound 尾-coil composed of two interacting subdomains.

The functional domain of MIR487A includes an N-terminal 伪-helix, a central 尾-sheet and a C-terminal domain. The N-terminal 伪-helix is 鈥嬧?媜ne of the functional domains of MIR487A and is composed of two interacting helices. These helices can interact, giving MIR487A a conserved structure of an N-terminal 伪-helix. The central 尾-page is another functional domain of MIR487A and has a conserved amino acid sequence. These conserved amino acid sequences include glutamic acid, asparagine, glutamine, and asparagine. These amino acids play a key role in the functional domain of MIR487A and may be involved in the function of MIR487A.

The C-terminal domain of MIR487A is a unique helical structure composed of two complementary helices. These helices can interact to impart secondary structure plasticity to the C-terminal domain of MIR487A. In addition, the C-terminal domain of MIR487A also has a conserved amino acid sequence, which includes glutamic acid, asparagine, glutamine, and asparagine. These amino acids play a key role in the C-terminal domain of MIR487A and may be involved in the function of MIR487A.

biological activity

MIR487A has a variety of biological activities. Studies have found that MIR487A can inhibit neuronal excitability, thereby having a potential therapeutic effect on neuronal damage and neurodegenerative diseases. In addition, MIR487A also has anti-tumor effects and can inhibit the growth and spread of tumor cells. These biological activities indicate that MIR487A has good therapeutic prospects and may become a new drug target.

Pharmacokinetics

Pharmacokinetics is an important field that studies the absorption, distribution, and excretion processes of drugs in the organism. As a protein, the pharmacokinetics of MIR487A mainly involve protein synthesis, expression and degradation processes. Protein synthesis occurs mainly in intracellular ribosomes, while expression occurs in intracellular ribosomes or the endoplasmic reticulum. In cells, MIR487A undergoes a series of degradation processes, including hydrolysis, salting out, and protease degradation. These degradation processes will affect the biological activity of MIR487A and affect the therapeutic effect of the drug.

Conclusion

MIR487A is a protein with multiple biological activities and can be used as a drug target. By analyzing its structure, it can be found that MIR487A has a conserved amino acid sequence and secondary structure, which provides important clues for drug development. In addition, MIR487A also has unique biological activities, indicating its potential as a drug.

Protein Name: MicroRNA 487a

The "MIR487A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR487A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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