Ribosomal Subunit Protein ES12: A Potential Drug Target Or Biomarker

Target Name: RPS12

NCBI ID: G6206

RPS12

Ribosomal Subunit Protein ES12: A Potential Drug Target Or Biomarker

Ribosomal subunit protein eS12 (RPS12) is a protein that is expressed in almost all eukaryotic cells and plays a critical role in protein synthesis. It is a key component of the ribosome, the protein machine that synthesizes proteins in the cell. RPS12 helps keep the ribosome in working order by interacting with several other proteins that are part of the same complex.

Recent studies have suggested that RPS12 may be a drug target or biomarker in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is because RPS12 has been shown to be involved in the regulation of cellular processes that are important in the development and progression of these diseases.

One of the key reasons for the potential clinical applications of RPS12 is its role in the regulation of protein synthesis. Many diseases are characterized by disruptions in the production of proteins, which can lead to a range of symptoms and complications. RPS12 plays a critical role in maintaining the stability and accuracy of protein synthesis by ensuring that the ribosome remains in working order.

In addition to its role in protein synthesis, RPS12 has also been shown to be involved in the regulation of cellular processes that are important in the development and progression of many diseases. For example, RPS12 has been shown to be involved in the regulation of the cytoskeleton, which is the structure that gives cells their shape and supports their mechanical forces. This suggests that RPS12 may be a useful target for drugs that are aimed at preventing or treating conditions that are characterized by changes in the cytoskeleton.

Another potential application of RPS12 is its role in the regulation of the cell cycle. The cell cycle is the process by which cells grow, divide, and replicate their genetic material. RPS12 plays a critical role in regulating the cell cycle by ensuring that proteins are synthesized and degraded at the correct times during the cell cycle. This is important for the proper functioning of the cell and is therefore of great interest in the development of cancer therapies.

In addition to its role in the cell cycle, RPS12 has also been shown to be involved in the regulation of many other cellular processes that are important in the development and progression of diseases. For example, RPS12 has been shown to be involved in the regulation of cell adhesion, which is the process by which cells stick together and form tissues. This suggests that RPS12 may be a useful target for drugs that are aimed at preventing or treating conditions that are characterized by changes in cell adhesion.

In conclusion, RPS12 is a protein that is expressed in almost all eukaryotic cells and plays a critical role in protein synthesis, cytoskeleton regulation, cell cycle regulation, and many other cellular processes that are important in the development and progression of diseases. Its clinical potential applications as a drug target or biomarker make it an attractive target for future research and development.

Protein Name: Ribosomal Protein S12

Functions: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797). Subunit of the 40S ribosomal complex (By similarity)

The "RPS12 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RPS12 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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