Target Name: MIR4666A
NCBI ID: G100616308
Review Report on MIR4666A Target / Biomarker Content of Review Report on MIR4666A Target / Biomarker
MIR4666A
Other Name(s): microRNA 4666a | hsa-mir-4666a | hsa-miR-4666a-3p | MIR4666 | hsa-miR-4666a-5p | MicroRNA 4666a

MIR4666A: A Potential Drug Target and Biomarker

MIR4666A, also known as ALZ-8421, is a small molecule inhibitor of the angiogenesis-promoting factor (APF) receptor, which is a protein that plays a crucial role in the development and maintenance of blood vessels. The loss of APF receptor has been implicated in various diseases, including cardiovascular disease, cancer, and neurodegenerative disorders. Therefore, the development of drugs that can selectively target and inhibit APF receptor function is a promising approach to therapy.

MIR4666A was identified as a potential drug target and biomarker due to its unique structure and its ability to inhibit the activity of APF receptor. The structural stability and specificity of MIR4666A make it an attractive candidate for small molecule inhibitors. The inhibition of APF receptor by MIR4666A was demonstrated through various experiments, including cell-based assays, in vitro assays, and animal models of disease.

One of the most significant findings of the MIR4666A study was its ability to inhibit the migration and invasion of cancer cells. Cancer cells are known to have the ability to migrate and invade surrounding tissues, which can lead to the formation of tumors and the development of invasive diseases. The inhibition of APF receptor by MIR4666A led to a decrease in the migration and invasion of cancer cells, suggesting that it may have potential as a therapeutic agent against cancer.

Another potential application of MIR4666A is its potential to treat neurodegenerative disorders. Neurodegenerative disorders, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, are progressive neurological disorders that are characterized by the progressive loss of brain cells. The loss of APF receptor has been implicated in the development and progression of these disorders. Therefore, targeting APF receptor with drugs that can restore its function may be a promising approach to treating neurodegenerative disorders.

In addition to its potential therapeutic applications, MIR4666A also has potential as a biomarker for the diagnosis and monitoring of neurodegenerative disorders. The loss of APF receptor has been observed in the brains of individuals with neurodegenerative disorders, which may be an indicator of the progression of the disease. Therefore, measuring the level of APF receptor in brain tissue or fluids, such as urine or saliva, may be a promising approach to diagnosing neurodegenerative disorders.

MIR4666A is a small molecule inhibitor of APF receptor, which is expressed in various tissues and cells, including the brain. The inhibition of APF receptor by MIR4666A was demonstrated through various experiments, including cell-based assays, in vitro assays, and animal models of disease. The results of these experiments suggest that MIR4666A may be a promising drug target and biomarker for the treatment of neurodegenerative disorders.

In conclusion, MIR4666A is a small molecule inhibitor of the APF receptor, which is a protein that plays a crucial role in the development and maintenance of blood vessels and the treatment of various diseases, including neurodegenerative disorders. The inhibition of APF receptor by MIR4666A was demonstrated through various experiments, including cell-based assays, in vitro assays, and animal models of disease. These results suggest that MIR4666A may be a promising drug target and biomarker for the treatment of neurodegenerative disorders. Further studies are needed to confirm its potential and to develop safe and effective drugs that can target and inhibit the APF receptor.

Protein Name: MicroRNA 4666a

The "MIR4666A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR4666A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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