MIR4735: A Potential Drug Target and Biomarker for Obesity (G100616363)
MIR4735: A Potential Drug Target and Biomarker for Obesity
Obesity is a significant public health issue, with over 20% of adults in the United States alone classified as obese. The number of obesity cases is projected to reach 35% by 2050, which will have a significant impact on overall health and quality of life. Additionally, obesity is a risk factor for various chronic diseases, including cardiovascular disease, diabetes, and certain cancers. MIR4735, a protein that has been identified as a potential drug target and biomarker for obesity, may provide new insights into the underlying causes of obesity and the development of effective treatments.
MIR4735 is a transmembrane protein that is expressed in various tissues and cells, including adipocytes, skeletal muscles, and neural cells. It is a member of the PPAR未 gene family, which is known for its role in modulating lipid metabolism and energy homeostasis. PPAR未 proteins are involved in the regulation of lipid oxidation, fatty acid oxidation, and the production of reactive oxygen species (ROS), which can contribute to the development of various diseases, including obesity.
MIR4735 has been shown to play a crucial role in the regulation of lipid metabolism and energy homeostasis. It is a potent inhibitor of lipid oxidation, which is the process by which free fatty acids are broken down and released into the bloodstream. MIR4735 has been shown to reduce lipid oxidation and increase the amount of stored fat, thereby contributing to the development of obesity.
In addition to its role in lipid metabolism, MIR4735 has also been shown to be involved in the regulation of energy homeostasis. It is a regulator of the succinyl-CoA synthetase, a critical enzyme in the citric acid cycle, which is responsible for generating energy in the form of ATP. MIR4735 has been shown to modulate the activity of succinyl-CoA synthetase, leading to a decrease in energy production and an increase in energy demand. This contributes to the development of obesity by promoting a state of energy excess, which can lead to overeating and other unhealthy lifestyle choices.
MIR4735 has also been shown to play a role in the regulation of inflammation. It is a co-factor for the nuclear factor kappa B (NF-kappa-B), a transcription factor that is involved in the regulation of inflammation and immune responses. MIR4735 has been shown to contribute to the regulation of NF-kappa-B activity, thereby contributing to the development of obesity as a result of inflammation.
In conclusion, MIR4735 is a protein that has been identified as a potential drug target and biomarker for obesity. Its role in modulating lipid metabolism, energy homeostasis, and inflammation may provide new insights into the underlying causes of obesity and the development of effective treatments. Further research is needed to fully understand the role of MIR4735 in obesity and to develop safe and effective treatments.
Protein Name: MicroRNA 4735
The "MIR4735 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR4735 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
MIR4736 | MIR4737 | MIR4738 | MIR4739 | MIR4740 | MIR4741 | MIR4742 | MIR4745 | MIR4746 | MIR4747 | MIR4749 | MIR4750 | MIR4751 | MIR4752 | MIR4753 | MIR4754 | MIR4755 | MIR4756 | MIR4757 | MIR4758 | MIR4759 | MIR4760 | MIR4761 | MIR4762 | MIR4763 | MIR4764 | MIR4765 | MIR4766 | MIR4767 | MIR4768 | MIR4769 | MIR4770 | MIR4771-1 | MIR4771-2 | MIR4772 | MIR4773-1 | MIR4773-2 | MIR4774 | MIR4775 | MIR4776-1 | MIR4776-2 | MIR4777 | MIR4778 | MIR4779 | MIR4780 | MIR4781 | MIR4782 | MIR4783 | MIR4784 | MIR4785 | MIR4786 | MIR4787 | MIR4789 | MIR4790 | MIR4791 | MIR4793 | MIR4794 | MIR4795 | MIR4796 | MIR4797 | MIR4798 | MIR4799 | MIR4800 | MIR4802 | MIR4803 | MIR4804 | MIR483 | MIR484 | MIR485 | MIR486-1 | MIR486-2 | MIR487A | MIR487B | MIR488 | MIR489 | MIR490 | MIR491 | MIR492 | MIR493 | MIR494 | MIR495 | MIR496 | MIR497 | MIR497HG | MIR498 | MIR4999 | MIR499A | MIR499B | MIR5000 | MIR5001 | MIR5002 | MIR5003 | MIR5004 | MIR5006 | MIR5007 | MIR5008 | MIR5009 | MIR500A | MIR500B | MIR501
