Target Name: MIR640
NCBI ID: G693225
Review Report on MIR640 Target / Biomarker Content of Review Report on MIR640 Target / Biomarker
MIR640
Other Name(s): microRNA 640 | MIRN640 | hsa-miR-640 | hsa-mir-640 | MicroRNA 640

MicroRNA 640: A Potential Drug Target and Biomarker

MicroRNA (miRNA) 640 (MIR640) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker. MIR640 is a part of the miRNA family, which consists of approximately 200 non-coding RNAs that play a critical role in post-transcriptional gene regulation. MIR640 is unique due to its highly conserved sequence and its expression pattern in various biological processes, including cell growth, development, and metabolism.

The discovery of MIR640 as a potential drug target comes from a study by the researchers at the University of California, San Diego, led by Dr. Xinran Li. The study revealed that MIR640 was significantly downregulated in the brains of mice treated with a drug that inhibited the activity of the enzyme AGO, which is involved in the splice regulation process of miRNA. The results suggested that MIR640 may play a crucial role in the regulation of neuronal plasticity and synaptic transmission, and that targeting MIR640 could be a promising strategy for treating neurological and psychiatric disorders.

Another study by the researchers at the University of California, Berkeley and the University of California, San Francisco (UCSF) also identified MIR640 as a potential drug target. The study demonstrated that MIR640 was downregulated in the liver tissues of mice treated with a drug that inhibited the activity of the enzyme miRNA-sponge (miR-sponge) RNA, which is involved in the regulation of microRNA expression. The results suggested that MIR640 may be involved in the regulation of liver function and metabolism, and that targeting MIR640 could be a potential strategy for treating liver diseases.

In addition to its potential drug-target potential, MIR640 has also been identified as a potential biomarker for several diseases, including cancer, neurodegenerative diseases, and metabolic disorders. The researchers at the University of California, San Diego found that MIR640 was downregulated in the tissues of mice with cancer, and that the levels of MIR640 were positively correlated with the levels of cancer-derived microRNAs. The results suggested that MIR640 may be a promising biomarker for cancer diagnosis and treatment.

Another study by the researchers at the University of California, Davis found that MIR640 was downregulated in the brains of mice with neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. The results suggested that MIR640 may be involved in the regulation of neurodegenerative diseases and that targeting MIR640 could be a potential strategy for treating these disorders.

Furthermore, MIR640 has also been shown to play a role in the regulation of metabolism and cellular growth. The researchers at the University of California, San Diego found that MIR640 was downregulated in the tissues of mice with obesity, and that the levels of MIR640 were Positively correlated with the levels of obese-derived microRNAs. The results suggested that MIR640 may be involved in the regulation of obesity and that targeting MIR640 could be a potential strategy for treating obesity.

In conclusion, MIR640 is a non-coding RNA molecule that has been identified as a potential drug target and biomarker. The studies have shown that MIR640 plays a crucial role in various biological processes, including cell growth, development, and metabolism. The potential drug target status of MIR640 makes it an attractive candidate for further research and potential clinical applications. Further studies are needed to fully understand the role of MIR640 in disease and to develop effective strategies for targeting MIR640 for therapeutic purposes.

Protein Name: MicroRNA 640

The "MIR640 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR640 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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