MIR6737: A Potential Drug Target and Biomarker (G102465441)
MIR6737: A Potential Drug Target and Biomarker
MIR6737 (hsa-miR-6737-3p) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. Its unique structure and expression pattern have made it an attractive target for researchers to study and develop new treatments.
MIR6737 is a microRNA (miRNA), a small non-coding RNA molecule that plays a crucial role in post-transcriptional gene regulation. It is expressed in various tissues and cells throughout the body and can interact with other molecules to regulate gene expression. The expression of MIR6737 is highly tissue- and cell-specific, which makes it an ideal candidate for studying the effects of drugs on specific tissues and cells.
One of the key features of MIR6737 is its unique structure. It is a small molecule that consists of only 19 amino acid residues and has a length of 5.9 kilobases (kb). Despite its small size, MIR6737 has a highly conserved core structure, which is typical of miRNAs. The conserved core structure consists of a head domain that contains the N-terminal amino acid residues and a tail domain that contains the C-terminal amino acid residues.
The N-terminal region of MIR6737 contains a unique feature that is typical of miRNAs. It contains a farnesylated cysteine residue, which is a modified form of the amino acid cysteine that can interact with the nuclear protein SIRT1. The farnesylated cysteine residue plays a crucial role in the stability and function of MIR6737, and is a potential target for drugs that target the N-terminal region.
The C-terminal region of MIR6737 is also unique. It contains a modified guanosine residue, which is commonly found in miRNAs. The modified guanosine residue is involved in the stability and function of MIR6737, and is a potential target for drugs that target this residue.
MIR6737 has been shown to play a role in various diseases, including cancer. For example, studies have shown that MIR6737 is downregulated in various types of cancer, and that inhibiting its expression can lead to increased cell proliferation and survival. This suggests that MIR6737 may be a useful biomarker for cancer and that its expression may be a potential drug target.
In addition to its potential as a drug target, MIR6737 has also been shown to be a potential biomarker for various diseases. For example, studies have shown that MIR6737 is downregulated in individuals with type 2 diabetes, and that increasing its expression can improve insulin sensitivity and reduce blood glucose levels. This suggests that MIR6737 may be a useful biomarker for type 2 diabetes.
In conclusion, MIR6737 is a unique and fascinating molecule that has the potential to be a drug target and biomarker for various diseases. Its conserved core structure and unique features make it an attractive target for researchers to study and develop new treatments. Further studies are needed to fully understand the role of MIR6737 in disease and to determine its potential as a drug target and biomarker.
Protein Name: MicroRNA 6737
The "MIR6737 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR6737 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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