MIDN: A Key Regulator of Cell Proliferation and Disease (G90007)
MIDN: A Key Regulator of Cell Proliferation and Disease
MIDN (Midnolin, transcript variant 2) is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidneys. MIDN is a key regulator of cell proliferation and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Despite its importance, much is still not known about MIDN and its function in the body.
The MIDN gene
MIDN is a member of the TATA-repeat transcription factor family, which is a group of proteins that are characterized by a conserved DNA-binding motif called a TATA-repeat sequence. This motif is present in the majority of eukaryotic genomes and is responsible for the regulation of gene expression.
MIDN functions
MIDN plays an important regulatory role in the cell cycle and is involved in many important biological processes, including cell proliferation, differentiation and tumor formation. During cell proliferation, MIDN controls the cell cycle by regulating the activity of cyclins and plays a key role in the progression and terminal stages of mitosis. During the differentiation process, MIDN promotes cell differentiation by regulating intracellular signaling pathways and participates in the formation of tissues and organs. In addition, MIDN also plays a role in tumor formation and is an important gene in the occurrence and progression of various tumors.
MIDN and disease
Abnormal expression of MIDN is closely related to the occurrence and development of various diseases. For example, overexpression of MIDN has been considered an important cause of many cancers, including liver cancer, lung cancer, breast cancer, and kidney cancer. In addition, MIDN is also associated with neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, and multiple sclerosis.
The treatment prospects of MIDN
As a potential drug target, MIDN has attracted the attention of many researchers. Many studies have shown that MIDN inhibitors can inhibit the growth and progression of tumor cells and show good anti-tumor effects in animal models. In addition, MIDN inhibitors can also improve the learning and memory abilities of neurodegenerative disease models, thereby providing new ideas for the treatment of these diseases.
Biological functions of MIDN
MIDN plays an important regulatory role in the cell cycle and participates in multiple biological processes such as cell proliferation, differentiation, and tumor formation. It controls the cell cycle by regulating the activity of cyclins and plays a key role in the progression and terminal stages of mitosis. In addition, MIDN also plays a role in tumor formation and is an important gene in the occurrence and progression of various tumors.
Abnormal expression of MIDN
Overexpression of MIDN has been considered to be an important cause of many cancers, including liver cancer, lung cancer, breast cancer, and kidney cancer. In addition, MIDN is also associated with neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, and multiple sclerosis.
The treatment prospects of MIDN
As a potential drug target, MIDN has attracted the attention of many researchers. Many studies have shown that MIDN inhibitors can inhibit the growth and progression of tumor cells and show good anti-tumor effects in animal models. In addition, MIDN inhibitors can also improve the learning and memory abilities of neurodegenerative disease models, thereby providing new ideas for the treatment of these diseases.
Conclusion
MIDN is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidneys. MIDN is a key regulator of cell proliferation and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Despite its importance, much is still not known about MIDN and its function in the body. The study of MIDN is expected to have a significant impact on our understanding of the biology of cell proliferation and the development of new treatments for a variety of diseases.
Protein Name: Midnolin
Functions: Facilitates ubiquitin-independent proteasomal degradation of polycomb protein CBX4. Plays a role in inhibiting the activity of glucokinase GCK and both glucose-induced and basal insulin secretion
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• general information;
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• protein biological mechanisms;
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• expression level;
• disease relevance;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
MIEF1 | MIEF2 | MIEN1 | MIER1 | MIER2 | MIER3 | MIF | MIF-AS1 | MIF4GD | MIGA1 | MIGA2 | MIIP | MILIP | MILR1 | MIMT1 | MINAR1 | MINAR2 | MINCR | MINDY1 | MINDY2 | MINDY2-DT | MINDY3 | MINDY4 | Minichromosome maintenance (MCM) 2-7 helicase complex | MINK1 | MINPP1 | MIOS | MIOX | MIP | MIPEP | MIPEPP3 | MIPOL1 | MIR1-1 | MIR1-1HG | MIR1-2 | MIR100 | MIR100HG | MIR101-1 | MIR101-2 | MIR10394 | MIR10396B | MIR10399 | MIR103A1 | MIR103A2 | MIR103B1 | MIR103B2 | MIR105-1 | MIR105-2 | MIR10527 | MIR106A | MIR106B | MIR107 | MIR10A | MIR10B | MIR11181 | MIR11400 | MIR11401 | MIR1178 | MIR1179 | MIR1180 | MIR1181 | MIR1182 | MIR1183 | MIR1184-1 | MIR1184-2 | MIR1184-3 | MIR1185-1 | MIR1185-2 | MIR1193 | MIR1197 | MIR1199 | MIR1200 | MIR1202 | MIR1203 | MIR1204 | MIR1205 | MIR1206 | MIR1207 | MIR1208 | MIR12129 | MIR12135 | MIR12136 | MIR122 | MIR1224 | MIR1225 | MIR1226 | MIR1227 | MIR1228 | MIR1229 | MIR1231 | MIR1233-1 | MIR1233-2 | MIR1234 | MIR1236 | MIR1237 | MIR1238 | MIR124-1 | MIR124-1HG | MIR124-2 | MIR124-2HG
