LMF2: A Drug Target for Lipid Biosynthesis (G91289)
LMF2: A Drug Target for Lipid Biosynthesis
Lipase maturation factor 2 (LMF2), also known as ISOform 1, is a protein that plays a crucial role in the maturation of lipids, including fats and oils, in the body. It is a key regulator of the lipid biosynthesis pathway, which is the process by which the body produces and consumes lipids. LMF2 is a cytoplasmic protein that is expressed in most tissues of the body, including the liver, adipose tissue, and muscle.
LMF2 is a member of the Lipase superfamily, an important family because they play a key role in biosynthesis. In this family, other members include LMF1 (lipase maturation factor 1) and LMF3 (lipase maturation factor 3). LMF2 plays a key role in the biosynthetic pathway, which is the process by which the body produces and consumes lipids.
The molecular structure domain of LMF2 includes an N-terminal 伪-helix, a central 尾-sheet and a C-terminal domain. The N-terminal 伪-helix is 鈥嬧?媡he main functional domain of LMF2 and is responsible for interacting with other proteins. The central beta page is a key part of LMF2 secondary structure and is responsible for interactions and localization with other proteins. The C-terminal domain includes a long equity helix that is responsible for binding to lipids.
The key role played by LMF2 in biosynthetic pathways makes it an attractive drug target. LMF2 has been used as a target for many drugs in animal models, including the treatment of hypercholesterolemia and obesity. In addition, LMF2 has also been used as a molecular marker to study lipid biosynthesis and metabolism.
The gene encoding LMF2 also encodes a transactivator. This transactivator can inhibit the activity of LMF2, making it a potential drug target. The transactivator of LMF2 can be used to study the effects of drugs on LMF2 and how LMF2 responds to drug treatment.
The biological function of LMF2 also makes it an important research molecule. Studying the role of LMF2 in biosynthetic pathways may shed light on lipid biosynthesis and metabolism
Protein Name: Lipase Maturation Factor 2
Functions: Involved in the maturation of specific proteins in the endoplasmic reticulum. May be required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway (By similarity)
The "LMF2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LMF2 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
LMLN | LMNA | LMNB1 | LMNB2 | LMNTD1 | LMNTD2 | LMNTD2-AS1 | LMO1 | LMO2 | LMO3 | LMO4 | LMO7 | LMO7-AS1 | LMO7DN | LMOD1 | LMOD2 | LMOD3 | LMTK2 | LMTK3 | LMX1A | LMX1B | LMX1B-DT | LNC-LBCS | LNCAROD | LNCARSR | LNCATV | LNCNEF | LNCOC1 | LNCOG | LNCPRESS1 | LNCRI | LNCRNA-ATB | LNCRNA-IUR | LNCTAM34A | LNP1 | LNPEP | LNPK | LNX1 | LNX1-AS1 | LNX2 | LOC100127946 | LOC100127955 | LOC100128002 | LOC100128028 | LOC100128050 | LOC100128059 | LOC100128079 | LOC100128093 | LOC100128164 | LOC100128242 | LOC100128288 | LOC100128317 | LOC100128361 | LOC100128398 | LOC100128494 | LOC100128593 | LOC100128770 | LOC100128966 | LOC100128988 | LOC100129034 | LOC100129098 | LOC100129148 | LOC100129175 | LOC100129203 | LOC100129215 | LOC100129316 | LOC100129381 | LOC100129434 | LOC100129455 | LOC100129534 | LOC100129603 | LOC100129697 | LOC100130000 | LOC100130207 | LOC100130285 | LOC100130298 | LOC100130331 | LOC100130452 | LOC100130463 | LOC100130548 | LOC100130587 | LOC100130691 | LOC100130698 | LOC100130744 | LOC100130748 | LOC100130872 | LOC100130899 | LOC100130938 | LOC100130987 | LOC100130992 | LOC100131096 | LOC100131107 | LOC100131257 | LOC100131289 | LOC100131372 | LOC100131496 | LOC100131532 | LOC100131626 | LOC100131635 | LOC100131859
