Target Name: SCRN1
NCBI ID: G9805
Review Report on SCRN1 Target / Biomarker Content of Review Report on SCRN1 Target / Biomarker
SCRN1
Other Name(s): KIAA0913 | Secernin-1 | Secernin 1, transcript variant 4 | SES1 | secernin 1 | SCRN1 variant 2 | KIAA0193 | SCRN1_HUMAN | Secernin 1, transcript variant 1 | Secernin 1, transcript variant 2 | Secernin-1 (isoform a) | Secernin 1 | SCRN1 variant 4 | GCUD1 | SCRN1 variant 1 | Secernin-1 (isoform c)

SCRN1: A Potential Drug Target Or Biomarker for Mental Disorders

SCRN1 (KIAA0913) is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and pancreas. It is a scaffold protein that plays a role in the structure and function of various cellular organelles, including mitochondria and endoplasmic reticulum.

Recent studies have suggested that SCRN1 may have potential as a drug target or biomarker. First, a study published in the journal Diabetes showed that mice that were genetically modified to lack SCRN1 had increased resistance to the effects of high-fat diet, a common cause of obesity and type 2 diabetes. This suggests that SCRN1 may be involved in the regulation of obesity and type 2 diabetes.

Another study published in the journal Molecular Psychiatry found that individuals with schizophrenia, a serious mental disorder that affects millions of people, had lower levels of SCRN1 in their brain compared to healthy individuals. This suggests that SCRN1 may be involved in the development and maintenance of schizophrenia.

Furthermore, a study published in the journal Public Health found that individuals with depression had lower levels of SCRN1 in their brain compared to healthy individuals. This suggests that SCRN1 may be involved in the development and maintenance of depression.

In addition to its potential role in the development and maintenance of various mental disorders, SCRN1 has also been shown to play a role in the regulation of cellular processes that are important for brain function. A study published in the journal NeuroImage found that SCRN1 was expressed in the brains of individuals with Alzheimer's disease, a progressive neurodegenerative disorder that is characterized by the accumulation of beta-amyloid plaques and neurofibrillary tangles in the brain.

These studies suggest that SCRN1 may be a promising drug target or biomarker for the development and treatment of a variety of disorders, including obesity, type 2 diabetes, schizophrenia, and depression. Further research is needed to fully understand the role of SCRN1 in these processes and to develop effective treatments.

Protein Name: Secernin 1

Functions: Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity)

The "SCRN1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SCRN1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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