TBKBP1: Key Regulator of Cell Growth and Differentiation (G9755)

Target Name: TBKBP1

NCBI ID: G9755

TBKBP1

TBKBP1: Key Regulator of Cell Growth and Differentiation

TBKBP1 (TBK1-binding protein 1) is a protein that is expressed in various tissues throughout the body, including the brain, heart, lungs, and gastrointestinal tract. It is a key regulator of cell growth and differentiation, and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the unique features of TBKBP1 is its ability to interact with the protein TBK1, which is also known as TSC1. TBK1 is a transcription factor that plays a critical role in regulating cell growth and survival, and is often mutated in a variety of diseases, including cancer.

Research has shown that TBKBP1 and TBK1 can form a complex that is physically and functionally important for the regulation of cell growth and differentiation. This complex plays a key role in the development and progression of many diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key functions of TBKBP1 is its ability to inhibit the activity of the transcription factor TGF-β, which is involved in the regulation of cell growth and differentiation. TGF-β is a potent regulator of cell growth and has been implicated in the development and progression of many diseases, including cancer.

In addition to its role in inhibiting TGF-β, TBKBP1 is also involved in the regulation of several other transcription factors, including NF-kappa-B, AP-1, and STAT3. These transcription factors are involved in the regulation of a wide range of cellular processes, including cell growth, differentiation, and inflammation.

The role of TBKBP1 in cancer is an area of active research. Many studies have shown that TBKBP1 is often mutated in many cancers, and that its expression is often reduced in these diseases. This suggests that TBKBP1 may be an attractive target for cancer therapies that target its regulation.

In addition to its role in cancer, TBKBP1 is also involved in the regulation of neurodegenerative diseases. For example, studies have shown that TBKBP1 is involved in the regulation of the neurotransmitter A尾, which is involved in the development of Alzheimer's disease.

In addition to its role in neurodegenerative diseases, TBKBP1 is also involved in the regulation of autoimmune disorders. For example, studies have shown that TBKBP1 is involved in the regulation of the immune response, and that its expression is often increased in individuals with autoimmune disorders.

Overall, TBKBP1 is a protein that is involved in a wide range of cellular processes that are important for the development and progression of many diseases. Its role in the regulation of cell growth and differentiation, as well as its involvement in the regulation of transcription factors, makes it an attractive target for a variety of therapies. Further research is needed to fully understand the role of TBKBP1 in disease, and to develop effective treatments.

Protein Name: TBK1 Binding Protein 1

Functions: Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity

The "TBKBP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TBKBP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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