TBX20: A Protein Regulating Cell Proliferation (G57057)

Target Name: TBX20

NCBI ID: G57057

TBX20

TBX20: A Protein Regulating Cell Proliferation

TBX20 is a protein that is expressed in many tissues of the human body, including the lungs, heart, kidneys, and brain. It is a member of the superfamily of transmembrane protein (SMP) family and is characterized by the presence of a long extracellular domain and a short intracellular domain.

TBX20 functions as a negative regulator of cell proliferation, which means that it works to prevent cells from growing and multiplying. This is important because an imbalance between cell proliferation and cell death can lead to the development of cancer.

One of the key functions of TBX20 is its role in the regulation of the cell cycle. It is a component of the G1-cell cycle protein complex, which is responsible for regulating the progress of cells through the cell cycle. This means that TBX20 helps to control the length of the S phase of the cell cycle, which is the stage of the cell cycle where the cell prepares for cell division.

Another important function of TBX20 is its role in the regulation of cell adhesion. It is a component of the cadherin gene family, which is responsible for the formation of tight junctions between cells. This helps to maintain the integrity of tissues and is important for many different functions in the body.

TBX20 is also involved in the regulation of cell survival. It has been shown to play a role in the regulation of cell survival by promoting the clearance of damaged or dysfunctional cells. This is important because the loss of cells can lead to the development of diseases such as cancer.

TBX20 is also a potential drug target. Its role in cell proliferation, cell adhesion, and cell survival make it an attractive target for drug development. Researchers are currently working to develop small molecules that can inhibit the activity of TBX20 and prevent it from functioning as a drug.

In addition to its potential as a drug target, TBX20 is also a potential biomarker. Its role in the regulation of cell proliferation and cell adhesion makes it an attractive candidate for use as a biomarker for a variety of diseases. For example, researchers are currently using RNA sequencing to identify differentially expressed genes in tissues of patients with cancer in order to identify potential biomarkers for cancer. If TBX20 is identified as one of these biomarkers, it could be used as a diagnostic tool or as a target for cancer therapies.

Overall, TBX20 is a protein that is expressed in many tissues of the human body and plays a critical role in the regulation of cell proliferation, cell adhesion, and cell survival. Its potential as a drug target and biomarker make it an attractive target for research into the mechanisms of disease.

Protein Name: T-box Transcription Factor 20

Functions: Acts as a transcriptional activator and repressor required for cardiac development and may have key roles in the maintenance of functional and structural phenotypes in adult heart

The "TBX20 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TBX20 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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