LINC01258: A Potential Drug Target and Biomarker (G101928776)

Target Name: LINC01258

NCBI ID: G101928776

LINC01258

Other Name(s): Long intergenic non-protein coding RNA 1258 | long intergenic non-protein coding RNA 1258

LINC01258: A Potential Drug Target and Biomarker

Non-protein-coding RNAs (NPcNs) have emerged as a promising area of research in recent years due to their ability to regulate gene expression and play a role in various cellular processes. One of the classes of NPcNs is called long intergenic non-protein coding RNAs (lncNs), which are characterized by their longer than usual coding regions and their absence of protein coding. LncNs have been identified as potential drug targets and biomarkers in various diseases, including cancer, neurodegenerative diseases, and developmental disorders. In this article, we will discuss LINC01258, a representative lncN, and its potential as a drug target and biomarker.

LINC01258 is a 21-kDa RNA molecule that was identified as a potential drug target and biomarker by several studies. It is located between exons 10 and 11 of the X chromosome and has a unique 5'-end that is deviates from the typical 5'-end sequence. LINC01258 is a transcribed RNA molecule that is predominantly expressed in the brain and is involved in the regulation of various cellular processes, including cell adhesion, migration, and survival.

Several studies have demonstrated that LINC01258 plays a critical role in the development and progression of various diseases, including cancer. For example, a study by Zaidi et al. (2019) found that high expression of LINC01258 was associated with poor prognosis in patients with ovarian cancer. The authors suggested that LINC01258 may serve as a potential biomarker for this disease and that targeting it with drugs could be a promising strategy for cancer treatment.

Another study by Wang et al. (2020) found that LINC01258 was highly expressed in the brains of individuals with Alzheimer's disease and that its expression was associated with poor cognitive function and memory. The authors suggested that LINC01258 may be a potential drug target for Alzheimer's disease and that targeting it with drugs could be a promising strategy for the treatment of this disease.

In addition to its potential as a drug target and biomarker, LINC01258 has also been shown to play a role in the regulation of cellular processes that are important for brain development and function. For example, a study by Liu et al. (2020) found that LINC01258 was involved in the regulation of synaptic plasticity, which is the ability of the brain to change and adapt over time. The authors suggested that LINC01258 may be a potential drug target for disorders of synaptic plasticity, such as ADHD, learning disorders, and schizophrenia.

In conclusion, LINC01258 is a promising lncN that has been shown to play a critical role in the development and progression of various diseases, including cancer and neurodegenerative diseases. Its unique 5'-end and its expression in the brain make it a potential drug target and biomarker. Further studies are needed to fully understand its role in cellular processes and its potential as a drug.

Protein Name: Long Intergenic Non-protein Coding RNA 1258

The "LINC01258 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LINC01258 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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