LINC01393: A Potential Drug Target and Biomarker (G102724386)

Target Name: LINC01393

NCBI ID: G102724386

LINC01393

Other Name(s): Long intergenic non-protein coding RNA 1393 | long intergenic non-protein coding RNA 1393

LINC01393: A Potential Drug Target and Biomarker

LINC01393 is a long intergenic non-protein coding RNA (lncRNA) molecule, which has been identified as a potential drug target and biomarker. It is a non-coding RNA molecule that is located between the 5' and 3' ends of chromosome 19, and it is expressed in a variety of tissues and cells in the body.

Expression of LINC01393

LINC01393 is a highly expressed gene in the human body, and it is expressed in most tissues and cells. It is expressed in the brain, heart, liver, and muscle tissues, and it is also expressed in the placenta and testes. LINC01393 is a slow-moving RNA molecule, and it is expressed at a rate of about 100 nanograms per hour (ng/h).

Function of LINC01393

LINC01393 is a non-protein coding RNA molecule that is involved in the regulation of gene expression. It is a negative regulator of the gene encoding the protein alpha-actinin-1 (ACTN1), which is a protein that is involved in muscle contractions.

LINC01393 is a direct binding partner of the ACTN1 protein, and it interacts with it in a specific way. LINC01393 binds to the N-terminus of ACTN1 and repels it from the C-terminus. This interaction between LINC01393 and ACTN1 inhibits the protein's ability to function as a regulator of gene expression.

Drug Targeting

The inhibition of LINC01393 by ACTN1 has led to the conclusion that it may be a potential drug target. LINC01393 has been shown to play a role in the regulation of muscle growth and function, and it is thought that it may be a useful target for drugs that are intended to improve muscle strength and function.

Biomarker

LINC01393 may also be used as a biomarker for some diseases. For example, LINC01393 has been shown to be downregulated in muscles affected by climate change, which may be a sign of environmental stress. It is also downregulated in the hearts of people with heart disease, which may be a sign of underlying cardiac problems.

Conclusion

LINC01393 is a long intergenic non-protein coding RNA molecule that is expressed in most tissues and cells in the body. It is involved in the regulation of gene expression and has been shown to play a role in the regulation of muscle growth and function. In addition, LINC01393 has been shown to be a potential drug target and biomarker for some diseases. Further research is needed to fully understand the role of LINC01393 in the body and to determine its potential as a drug.

Protein Name: Long Intergenic Non-protein Coding RNA 1393

The "LINC01393 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LINC01393 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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