LINC01224: A Long Intergenic Non-Protein Coding RNA (G104472717)

Target Name: LINC01224

NCBI ID: G104472717

LINC01224

Other Name(s): long intergenic non-protein coding RNA 1224 | Long intergenic non-protein coding RNA 1224, transcript variant 1

LINC01224: A Long Intergenic Non-Protein Coding RNA

LINC01224 is a long intergenic non-protein coding RNA (lncRNA) that has been identified in various studies as a potential drug target and biomarker. It is a non-coding RNA molecule that is expressed in a variety of tissues and cells, including the brain, heart, and gastrointestinal tract. The function of LINC01224 is not well understood, but it is believed to play a role in the regulation of cellular processes, such as cell growth, differentiation, and survival.

Drug Target Potential

LINC01224 has been identified as a potential drug target due to its unique structure and the involvement of various signaling pathways. LINC01224 is a long non-coding RNA molecule that contains a unique open reading frame (ORF) that is composed of 29 amino acid residues. It is located in the cytoplasm and has been shown to interact with various protein molecules, including the transcription factor, p53.

The interaction between LINC01224 and p53 is thought to play a crucial role in the regulation of cellular processes, such as cell growth, apoptosis, and DNA damage repair. LINC01224 has been shown to physically interact with p53 through its ORF, leading to the formation of a protein-RNA complex that is involved in the regulation of p53 activity.

In addition to its interaction with p53, LINC01224 has also been shown to interact with other transcription factors, including NF-kappa-B and HIF1?±. These interactions may contribute to the regulation of cellular processes, such as cell growth, differentiation, and survival.

Biomarker Potential

The potential use of LINC01224 as a biomarker is based on its expression and/or activity in various tissues and cell types. LINC01224 has been shown to be expressed in a variety of tissues, including the brain, heart, and gastrointestinal tract. It is also known to be expressed in various cell types, such as neurons, muscle cells, and cancer cells.

In addition to its expression, LINC01224 has also been shown to play a role in cellular processes, such as cell growth, apoptosis, and DNA damage repair. LINC01224 has been shown to physically interact with various protein molecules, including the transcription factor, p53. These interactions may contribute to the regulation of cellular processes and may be potential biomarkers for various diseases.

Conclusion

LINC01224 is a long intergenic non-protein coding RNA that has been identified as a potential drug target and biomarker. Its unique structure and interaction with various protein molecules, including the transcription factor, p53, suggest that it plays a critical role in the regulation of cellular processes, such as cell growth, apoptosis, and DNA damage repair. Further research is needed to fully understand the function of LINC01224 and its potential as a drug target and biomarker.

Protein Name: Long Intergenic Non-protein Coding RNA 1224

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•   general information;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
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