LOC105375275: A Potential Drug Target and Biomarker (G105375275)
LOC105375275: A Potential Drug Target and Biomarker
LOC105375275 is a novel protein that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an attractive target for researchers to study and develop new treatments.
LOC105375275 is a member of the LOC105 family, which is known for its role in various cellular processes, including cell signaling, DNA replication, and chromatin structure. LOC105375275 is characterized by a unique structure that consists of a long N-terminus, a transmembrane segment , and a C-terminus. The N-terminus of LOC105375275 contains a unique domain that is composed of a nucleotide-binding oligomerization (NBO) domain and a leucine-rich repeat (LRR) domain.
The NBO domain is a common protein domain that is found in various proteins and is known for its ability to interact with nucleotides. In LOC105375275, the NBO domain is used to interact with microtubules, which are important for cell signaling and transport. This interaction between the NBO domain and microtubules suggest that LOC105375275 may be involved in regulating cellular processes that are regulated by microtubules.
The LRR domain is a common protein domain that is found in various proteins and is known for its ability to interact with other proteins. In LOC105375275, the LRR domain is used to interact with the protein Kinesin-2, which is a key regulator of microtubules . This interaction between LOC105375275 and Kinesin-2 suggests that LOC105375275 may be involved in regulating microtubule dynamics and stability.
LOC105375275 has been shown to interact with various microtubule-associated proteins (MAPs), including Kinesin-2, M-tubulin-1 (MAP-1), and N-macrophage-1 (MAP-N). This interaction with MAPs suggests that LOC105375275 may be involved in regulating microtubule dynamics and stability, which are critical for various cellular processes.
In addition to its interaction with MAPs, LOC105375275 has also been shown to interact with other proteins that are involved in cellular signaling and development, including the transcription factor p53 and the protein heat shock protein (Hsp)70. This interaction with p53 and Hsp70 suggests that LOC105375275 may be involved in regulating cellular processes that are regulated by these transcription factors.
LOC105375275 has also been shown to play a role in various cellular processes, including cell division, apoptosis, and cellular signaling. For example, LOC105375275 has been shown to be involved in regulating the entry of neurons into the cell membrane, which is critical for their survival and function. Additionally, LOC105375275 has been shown to play a role in regulating cellular signaling pathways, including the NF-kappa pathway, which is involved in cell growth, differentiation, and survival.
In conclusion, LOC105375275 is a unique protein that has been identified as a potential drug target and biomarker for various diseases. Its unique structure and function have made it an attractive target for researchers to study and develop new treatments. Further research is needed to fully understand the role of LOC105375275 in
Protein Name: Uncharacterized LOC105375275
The "LOC105375275 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105375275 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
LOC105375284 | LOC105375291 | LOC105375310 | LOC105375337 | LOC105375340 | LOC105375341 | LOC105375347 | LOC105375361 | LOC105375379 | LOC105375381 | LOC105375404 | LOC105375410 | LOC105375423 | LOC105375428 | LOC105375429 | LOC105375434 | LOC105375440 | LOC105375443 | LOC105375448 | LOC105375451 | LOC105375452 | LOC105375490 | LOC105375492 | LOC105375494 | LOC105375508 | LOC105375523 | LOC105375536 | LOC105375541 | LOC105375543 | LOC105375552 | LOC105375556 | LOC105375567 | LOC105375574 | LOC105375597 | LOC105375600 | LOC105375610 | LOC105375623 | LOC105375629 | LOC105375631 | LOC105375639 | LOC105375655 | LOC105375670 | LOC105375672 | LOC105375683 | LOC105375690 | LOC105375704 | LOC105375712 | LOC105375716 | LOC105375721 | LOC105375725 | LOC105375730 | LOC105375733 | LOC105375739 | LOC105375741 | LOC105375743 | LOC105375745 | LOC105375751 | LOC105375753 | LOC105375755 | LOC105375779 | LOC105375785 | LOC105375787 | LOC105375805 | LOC105375825 | LOC105375836 | LOC105375855 | LOC105375856 | LOC105375861 | LOC105375875 | LOC105375896 | LOC105375903 | LOC105375911 | LOC105375914 | LOC105375920 | LOC105375922 | LOC105375925 | LOC105375928 | LOC105375931 | LOC105375938 | LOC105375943 | LOC105375951 | LOC105375962 | LOC105375974 | LOC105375976 | LOC105375977 | LOC105375983 | LOC105375984 | LOC105375990 | LOC105375999 | LOC105376001 | LOC105376014 | LOC105376017 | LOC105376035 | LOC105376081 | LOC105376107 | LOC105376110 | LOC105376136 | LOC105376139 | LOC105376156 | LOC105376157
