LOC105376081: A Potential Drug Target for Tight Junction Regulation

LOC105376081: A Potential Drug Target for Tight Junction Regulation

LOC105376081 (LOC105376081 variant X3) is a protein that is expressed in various tissues of the human body, including the brain, heart, and blood vessels. It is a member of the integrin alpha-2 (ITGA2) family, which is a group of transmembrane proteins that are involved in cell-cell and cell-extracellular matrix adhesion.

LOC105376081 variant X3 is a specific variant of the ITGA2 gene that has been identified as a potential drug target or biomarker. The ITGA2 gene is known to be involved in the development and maintenance of tight junctions, which are specialized cell-cell junctions that are responsible for ensuring the proper delivery of materials into and out of cells.

Tight junctions are critical for maintaining the integrity of the intercellular space and have been implicated in a number of physiological processes, including the regulation of ion and solute transport, as well as the maintenance of cell shape and the regulation of cell-cell interactions. Alterations in tight junction structure or function have been implicated in a wide range of diseases, including cancer, neurodegenerative diseases, and developmental disorders.

LOC105376081 variant X3 has been shown to be involved in the regulation of tight junction structure and function. Studies have shown that LOC105376081 is a critical regulator of the desmosome, a protein that is involved in the formation and maintenance of tight junctions. The desmosome is a complex that is composed of multiple proteins that help to ensure the proper formation and maintenance of tight junctions.

In addition to its role in tight junction regulation, LOC105376081 has also been shown to be involved in the regulation of cell adhesion and in the development of cancer. Studies have shown that LOC105376081 is involved in the regulation of cell adhesion and that alterations in its function have been implicated in the development of a variety of cancer types.

The potential drug target or biomarker that LOC105376081 represents is its involvement in the regulation of tight junction structure and function. This is an area of ongoing research and there is a high demand for compounds that can modulate the activity of LOC105376081. The development of small molecules that can modulate LOC105376081 activity could lead to new treatments for a variety of diseases, including cancer, neurodegenerative diseases, and developmental disorders.

Protein Name: Uncharacterized LOC105376081

The "LOC105376081 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105376081 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

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