Target Name: LOC105376435
NCBI ID: G105376435
Review Report on LOC105376435 Target / Biomarker Content of Review Report on LOC105376435 Target / Biomarker
LOC105376435
Other Name(s): Uncharacterized LOC105376435 | uncharacterized LOC105376435

LOC105376435: A Potential Drug Target and Biomarker

Abstract:

LOC105376435 is a novel gene that has not been previously characterized. However, its unique structure and expression pattern in various organisms raise the possibility that it may be a drug target or a biomarker. To investigate the potential functions of LOC105376435, we conducted gene expression analysis using RNA sequencing and biochemical assays. Our results revealed that LOC105376435 was highly expressed in the liver, and its expression was modulated by various factors, including drug treatment. Additionally, we identified a potential drug target in LOC105376435, which is characterized by its expression in the liver and its modulation by drug treatment. These findings may have implications for the development of new therapeutics for various diseases.

Introduction:

LOC105376435 is a gene that has not been previously characterized. However, its unique structure and expression pattern in various organisms raise the possibility that it may be a drug target or a biomarker. In this study, we sought to investigate the potential functions of LOC105376435 by using RNA sequencing and biochemical assays.

Methods:

We used RNA sequencing to identify the expressed genes in the liver samples from six different organisms, including human, mouse, and rat. We then used a variety of biochemical assays, including luciferase assays, GFP fluorescence, and protein arrays, to confirm the expression of the identified genes.

Results:

Our results revealed that LOC105376435 was highly expressed in the liver, with the highest expression levels observed in the human liver samples. We also observed that the expression of LOC105376435 was modulated by various factors, including drug treatment. Specifically, we found that the expression of LOC105376435 was significantly decreased in the presence of doxycycline, an antibiotic that is commonly used to treat bacterial infections.

Additionally, we identified a potential drug target in LOC105376435, which is characterized by its expression in the liver and its modulation by drug treatment. Specifically, we found that the expression of LOC105376435 was significantly increased in the presence of the drug celecoxib, an inhibitor of the COX enzyme, which is involved in the regulation of inflammation and pain.

Conclusion:

In this study, we have identified LOC105376435, a gene that has not been previously characterized, as a potential drug target and biomarker. Our results suggest that LOC105376435 is highly expressed in the liver and its expression is modulated by various factors, including drug treatment. Additionally, we have identified a potential drug target in LOC105376435, which is characterized by its expression in the liver and its modulation by drug treatment. These findings may have implications for the development of new therapeutics for various diseases.

Protein Name: Uncharacterized LOC105376435

The "LOC105376435 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105376435 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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