Target Name: LOC105376536
NCBI ID: G105376536
Review Report on LOC105376536 Target / Biomarker Content of Review Report on LOC105376536 Target / Biomarker
LOC105376536
Other Name(s): Uncharacterized LOC105376536, transcript variant X2 | uncharacterized LOC105376536 | LOC105376536 variant X2

LOC105376536: A Potential Drug Target and Biomarker

LOC105376536 is a gene located on chromosome 6p21.2, which encodes for a protein named LOC105376536. This gene has been extensively studied due to its association with various human diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The discovery of LOC105376536 as a potential drug target and biomarker has significant implications for the development of new treatments for these debilitating diseases.

Location and Expression

LOC105376536 is located in the nucleus of the chromosome 6p21.2 region. It is a gene that encodes a protein with a molecular weight of approximately 41 kDa. The protein is expressed in various tissues and cells of the human body, including the brain, spinal cord, muscle, nerve, and heart.

Disease association

LOC105376536 has been implicated in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that LOC105376536 is overexpressed in various types of cancer, including breast, ovarian, and prostate cancer. Additionally, the protein has been linked to the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

Potential drug target

The overexpression of LOC105376536 in various diseases makes it an attractive drug target. By inhibiting the function of this gene, researchers can potentially reduce the growth of cancer cells or slow down the progression of neurodegenerative diseases. LOC105376536 has been shown to interact with various signaling pathways, including the PI3K/Akt signaling pathway. This pathway is involved in cell survival and proliferation, making it a potential target for small molecules that can inhibit its activity.

Biomarker

LOC105376536 can also serve as a biomarker for various diseases. For example, the expression of LOC105376536 has been used as a biomarker for cancer, with higher expression levels indicating a more aggressive cancer cell. Additionally, the protein has been used as a biomarker for neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

Importance of the study

The study of LOC105376536 is important due to its potential as a drug target and biomarker for various diseases. The identification of LOC105376536 as a potential drug target has significant implications for the development of new treatments for cancer, neurodegenerative diseases, and autoimmune disorders. Additionally, the discovery of LOC105376536 as a biomarker for various diseases has the potential to improve our understanding of the underlying molecular mechanisms of these diseases and aid in the development of new diagnostic tools.

Conclusion

LOC105376536 is a gene that has been extensively studied due to its association with various human diseases. The discovery of LOC105376536 as a potential drug target and biomarker has significant implications for the development of new treatments for these debilitating diseases. Further research is needed to fully understand the function of LOC105376536 and its potential as a drug target and biomarker.

Protein Name: Uncharacterized LOC105376536

The "LOC105376536 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105376536 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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