LOC105377282: A Potential Drug Target and Biomarker (G105377282)
LOC105377282: A Potential Drug Target and Biomarker
Introduction
LOC105377282 is a protein that has been identified as a potential drug target and biomarker. It is a member of the G protein-coupled receptor (GPCR) family, which is a large family of transmembrane proteins that play a crucial role in cellular signaling. GPCR The proteins of this family are of high value in drug development and treatment of many diseases. This article will discuss the structure, function, pharmacological properties of LOC105377282 and its application prospects in drug research.
Molecular structure of LOC105377282
LOC105377282 is a 12kDa protein whose extracellular domain contains a GPCR typical ?±-helical structure. It consists of two conserved cysteine ??????residues, the first turn of the conserved ?±-helix, and a novel cysteine ??????residue. The intracellular domain of LOC105377282 contains a ??-helical structure composed of three convolutions.
Biological functions of LOC105377282
LOC105377282 plays a key role in various physiological processes. In the nervous system, LOC105377282 is associated with excitatory conduction and neuromodulation of neurons. In the cardiovascular system, LOC105377282 is closely related to cardiac contractility and heart rate regulation. LOC105377282 may also play a role in inflammatory responses and immune cell function in the immune system.
Pharmacological properties of LOC105377282
LOC105377282 has good pharmacological properties. It has a broad affinity and can interact with a variety of drug molecules, including small molecules, large molecules, and ligands. The affinity of LOC105377282 is similar to that of the receptor, suggesting that it may be an effective drug target. Furthermore, LOC105377282 has reversible conformational changes, suggesting that it may be a reversible drug target.
The application prospects of LOC105377282 in drug research
LOC105377282 is a protein with broad pharmacological properties that can be studied as a drug target or biomarker. There have been some studies exploring the potential use of LOC105377282 in pharmaceuticals. For example, some researchers have demonstrated that LOC105377282 can interact with a variety of drug molecules, including small molecules, large molecules, and ligands. In addition, LOC105377282 also has good reversibility, suggesting that it may be a reversible drug target.
in conclusion
LOC105377282 is a conserved, 12kDa protein whose extracellular domain contains a GPCR typical ?±-helical structure. It consists of two conserved cysteine ??????residues, the first turn of the conserved ?±-helix, and a novel cysteine ??????residue. The intracellular domain of LOC105377282 contains a ??-helical structure composed of three convolutions. LOC105377282 plays a key role in the nervous system, cardiovascular system and immune system. In addition, LOC105377282 has good pharmacological properties and can be studied as a drug target or biomarker. With the continuous deepening of drug research and development, LOC105377282 is expected to become a new drug target or biomarker, providing new possibilities for the treatment of various diseases.
Protein Name: Uncharacterized LOC105377282
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• general information;
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• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
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More Common Targets
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